Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   V6U67_RS00315 Genome accession   NZ_CP145865
Coordinates   51340..53283 (+) Length   647 a.a.
NCBI ID   WP_022495805.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS8     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 46340..58283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS00285 (V6U67_00285) argR 46545..46973 (+) 429 WP_170314548.1 arginine repressor -
  V6U67_RS00290 (V6U67_00290) - 46973..47332 (+) 360 WP_002889586.1 YlbF family regulator -
  V6U67_RS00295 (V6U67_00295) hexA 47352..49883 (+) 2532 WP_410531299.1 DNA mismatch repair protein MutS Machinery gene
  V6U67_RS00300 (V6U67_00300) - 49917..50372 (-) 456 WP_014633774.1 DUF3021 domain-containing protein -
  V6U67_RS00305 (V6U67_00305) brsR 50369..50806 (-) 438 WP_014633775.1 LytTR family DNA-binding domain-containing protein Regulator
  V6U67_RS00310 (V6U67_00310) - 50985..51290 (+) 306 WP_002886319.1 hypothetical protein -
  V6U67_RS00315 (V6U67_00315) hexB 51340..53283 (+) 1944 WP_022495805.1 DNA mismatch repair endonuclease MutL Machinery gene
  V6U67_RS00320 (V6U67_00320) - 53414..53635 (+) 222 WP_022495804.1 hypothetical protein -
  V6U67_RS00325 (V6U67_00325) ruvA 53793..54383 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA Machinery gene
  V6U67_RS00330 (V6U67_00330) - 54392..54946 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  V6U67_RS00335 (V6U67_00335) cinA 55043..56311 (+) 1269 WP_014633777.1 competence/damage-inducible protein A Machinery gene
  V6U67_RS00340 (V6U67_00340) recA 56347..57486 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  V6U67_RS00345 (V6U67_00345) spx 57654..58052 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72501.59 Da        Isoelectric Point: 5.2049

>NTDB_id=853681 V6U67_RS00315 WP_022495805.1 51340..53283(+) (hexB) [Streptococcus salivarius strain KSS8]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGAAKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLISESESPVSLVENKP
QPSVKQAQRSADEGDSEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=853681 V6U67_RS00315 WP_022495805.1 51340..53283(+) (hexB) [Streptococcus salivarius strain KSS8]
ATGCCAAAAATCATCGAATTACCTGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGCCCAGCCAGTGT
TGTTAAAGAGTTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGATAATGGCGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGACCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACCTATTTTATAATACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTCCGTCAAGCTATTGCTGGTATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAGATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTCCCTATTGCGGTTATTGATATTCAGATTGATCCTTATT
TGGCTGATGTCAATGTTCACCCAACCAAGCAGGAAGTACGTATTTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGAGGTGC
AGCTAAGCCAGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTATATCGGAGTCAGAGTCTCCAGTTTCATTGGTAGAAAACAAACCG
CAACCTTCTGTTAAACAGGCACAGCGTTCAGCAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAACTCTGGACAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATTGGTGAGGTTGACAGCAGTTTACAGCAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCAGACTACATTAGTTTACAAGAAAAAATGTCCCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAACAACA
CTTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTT
CTTTTGACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTC
ACGGACGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACGAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.512

100

0.705