Detailed information NTG0853679

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6U67_RS00295
• Genome accession: NZ_CP145865
• Coordinates: 47352..49883 (+)
• Length: 843 a.a.
• NCBI ID: WP_410531299.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS8
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 42352..54883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U67_RS00275 (V6U67_00275)	purB	42525..43823 (+)	1299	WP_002886310.1	adenylosuccinate lyase	-
V6U67_RS00280 (V6U67_00280)	argS	44699..46390 (-)	1692	WP_002889584.1	arginine--tRNA ligase	-
V6U67_RS00285 (V6U67_00285)	argR	46545..46973 (+)	429	WP_170314548.1	arginine repressor	-
V6U67_RS00290 (V6U67_00290)	-	46973..47332 (+)	360	WP_002889586.1	YlbF family regulator	-
V6U67_RS00295 (V6U67_00295)	hexA	47352..49883 (+)	2532	WP_410531299.1	DNA mismatch repair protein MutS	Machinery gene
V6U67_RS00300 (V6U67_00300)	-	49917..50372 (-)	456	WP_014633774.1	DUF3021 domain-containing protein	-
V6U67_RS00305 (V6U67_00305)	brsR	50369..50806 (-)	438	WP_014633775.1	LytTR family DNA-binding domain-containing protein	Regulator
V6U67_RS00310 (V6U67_00310)	-	50985..51290 (+)	306	WP_002886319.1	hypothetical protein	-
V6U67_RS00315 (V6U67_00315)	hexB	51340..53283 (+)	1944	WP_022495805.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6U67_RS00320 (V6U67_00320)	-	53414..53635 (+)	222	WP_022495804.1	hypothetical protein	-
V6U67_RS00325 (V6U67_00325)	ruvA	53793..54383 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94684.88 Da
• Isoelectric Point: 4.6783

>NTDB_id=853679 V6U67_RS00295 WP_410531299.1 47352..49883(+) (hexA) [Streptococcus salivarius strain KSS8]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLVEMGYKVAIA
EQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVLGYYLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGIATLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVIAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATLNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIRPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=853679 V6U67_RS00295 WP_410531299.1 47352..49883(+) (hexA) [Streptococcus salivarius strain KSS8]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTATCATTCAGCTCAAGCCTATATTGATGTCTTGGTTGAGATGGGGTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAAAAGGCTGTTGGTGTGGTTAAGCGTGAGGTTGTTCAGGTTATCACCCCAGGAACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAATAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGATTCGGCCTAGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAATTGGATGATTTCAGTTCTGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTGCTTGGTTATTATTTACCTGAAGCTGATGAACAAGTTTTGGTGAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGTGAATTAAGCCATTTACAAAAGGCACAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCGAGTTTGGATTTACTGGAAAATGCTAGAACAGGTAAGAAACACGGTTCTCTTTT
CTGGCTCCTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGTACTTGGATTGACCGTCCTTTAGTGAATCAGG
CTGCCATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGATCTGACTGAGAGTCTT
AAAGGGGTTTACGATATTGAGCGACTGGCCAGTCGTGTTTCCTTTGGAAAGGCTAATCCTAAAGATTTGATTCAGCTAGG
TCATACCCTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATGACGAGGCCTTGTCACGTCTTTTACAAG
AGCTAGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATTGATCCCGATGCTCCAGCAACCATTACAGAAGGT
GGTATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGCGAGGGGACGTCATGGATCGCAGA
CATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTGCAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAACTCAGAGCGTTTTGGA
ACTGCCGAGTTGGCTAAGATTGAAGGTGAGATGCTTGAGGCACGTGAAAAGTCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCTATTGCGACAGTCGATGTGCTTC
AGAGTTTGGCTGTTATAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAACATCGTATCGTTATTGATCAA
GGTCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCAGACCAA
TGTTCAGCTCATTACTGGGCCAAATATGAGTGGTAAATCTACTTATATGCGTCAGTTGGCCTTGTCAGTCGTTATGGCTC
AGATGGGGTCTTATGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCCATCTATACACGTATTGGTGCTGCAGAT
GACTTGATTTCAGGTCAGTCAACCTTCATGGTTGAGATGATGGAGGCTAACCAGGCAATTAAACGGGCAACACTTAATTC
CTTGATTATTTTTGATGAGTTGGGGCGTGGAACAGCCACCTACGATGGTATGGCTTTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTAGAGGGCGAGACAGTTACCATCCGACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCAGCCACTGAAACACATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGAGTTACGTGATTTGGACATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCGGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (117-230)

• MutS domain I (MutS_I) (1-109)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain III (MutS_III) (247-537)

• MutS domain V (MutS_V) (590-776)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.815	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	36.311	100	0.371