Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   V6T26_RS09905 Genome accession   NZ_CP145858
Coordinates   2106887..2108830 (-) Length   647 a.a.
NCBI ID   WP_410541265.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS11     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2101887..2113830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS09875 (V6T26_09860) spx 2102115..2102513 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  V6T26_RS09880 (V6T26_09865) recA 2102681..2103820 (-) 1140 WP_002889600.1 recombinase RecA Machinery gene
  V6T26_RS09885 (V6T26_09870) cinA 2103861..2105126 (-) 1266 WP_410533800.1 competence/damage-inducible protein A Machinery gene
  V6T26_RS09890 (V6T26_09875) - 2105223..2105777 (-) 555 WP_073951167.1 DNA-3-methyladenine glycosylase I -
  V6T26_RS09895 (V6T26_09880) ruvA 2105786..2106376 (-) 591 WP_013989915.1 Holliday junction branch migration protein RuvA Machinery gene
  V6T26_RS09900 (V6T26_09885) - 2106534..2106755 (-) 222 WP_073690141.1 hypothetical protein -
  V6T26_RS09905 (V6T26_09890) hexB 2106887..2108830 (-) 1944 WP_410541265.1 DNA mismatch repair endonuclease MutL Machinery gene
  V6T26_RS09910 (V6T26_09895) - 2108882..2109187 (-) 306 WP_410541266.1 hypothetical protein -
  V6T26_RS09915 (V6T26_09900) - 2109366..2109803 (+) 438 WP_013989911.1 LytTR family DNA-binding domain-containing protein -
  V6T26_RS09920 (V6T26_09905) - 2109800..2110255 (+) 456 WP_060972120.1 DUF3021 domain-containing protein -
  V6T26_RS09925 (V6T26_09910) hexA 2110289..2112847 (-) 2559 WP_410541267.1 DNA mismatch repair protein MutS Machinery gene
  V6T26_RS09930 (V6T26_09915) - 2112840..2113199 (-) 360 WP_410541268.1 YlbF family regulator -
  V6T26_RS09935 (V6T26_09920) argR 2113199..2113627 (-) 429 WP_171963598.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72534.62 Da        Isoelectric Point: 5.2831

>NTDB_id=853112 V6T26_RS09905 WP_410541265.1 2106887..2108830(-) (hexB) [Streptococcus salivarius strain KSS11]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGATKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESESSVSSVENKP
QPTVKQAKRLADDSDSEHEKLDYKNKSKMKRMLENLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMALLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=853112 V6T26_RS09905 WP_410541265.1 2106887..2108830(-) (hexB) [Streptococcus salivarius strain KSS11]
ATGCCAAAAATCATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGAGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATTACAGACAATGGCGAAGGAATGGCTCAAGCTGACGTGGCTATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGACCTCTTTCGTATTCGAACTCTTGGTTTTCGAGGTGAGGCCCTGCCATCAATAGCTTCTATCAG
TCATCTTACCATTGTGACGGCGGCTGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACTTATTTTATAATACCCCTGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCCGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAAGTTGCCTT
CACCTTGCTTAATGACGGCCGTCAGTTGACACAGACCTCAGGTACTGGAGACCTCCGTCAAGCTATTGCCGGGATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAAATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGCTATGTTAGTCTCCCT
GAGTTGACCCGTGCGAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATAAAAAACTTCCTACTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGGCGCTTCCCTATTGCGGTTATTGATATTCAAATTGATCCCTATT
TGGCTGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAGGAGCTTATGGCCCTCATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACTAGAGGTGC
AACTAAGCCGGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTTCAAGAGGATATCAAACCTCTTGTATCAGAGTCAGAGTCTTCAGTTTCATCGGTAGAAAACAAACCG
CAACCTACTGTTAAACAGGCAAAACGTTTAGCAGATGATAGTGATAGTGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAAATCTGGACAATGAGGAAACATCAACCTTCCCTGAGTTGGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCTCAAGGACAAGGTGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATTGGTGAGGTTGACAGTAGCTTACAACAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCGGATTACATTAGTTTACAAGAAAAAATGGCTCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAACA
CCTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCTGCAGTCTATGAGATGTGCGACATGCTT
CTTTTGACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTGCAGCTTGCACAGTGTAAAAACCCCTACAATTGCCCTC
ACGGACGTCCTGTACTTGTCAACTTTACAAAGTCTGATATGGAAAAAATGTTCCGTCGAATTCAAGAAAATCATACTAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(448-591)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70

100

0.703