Detailed information NTG0853113

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6T26_RS09925
• Genome accession: NZ_CP145858
• Coordinates: 2110289..2112847 (-)
• Length: 852 a.a.
• NCBI ID: WP_410541267.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS11
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2105289..2117847

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6T26_RS09895 (V6T26_09880)	ruvA	2105786..2106376 (-)	591	WP_013989915.1	Holliday junction branch migration protein RuvA	Machinery gene
V6T26_RS09900 (V6T26_09885)	-	2106534..2106755 (-)	222	WP_073690141.1	hypothetical protein	-
V6T26_RS09905 (V6T26_09890)	hexB	2106887..2108830 (-)	1944	WP_410541265.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6T26_RS09910 (V6T26_09895)	-	2108882..2109187 (-)	306	WP_410541266.1	hypothetical protein	-
V6T26_RS09915 (V6T26_09900)	-	2109366..2109803 (+)	438	WP_013989911.1	LytTR family DNA-binding domain-containing protein	-
V6T26_RS09920 (V6T26_09905)	-	2109800..2110255 (+)	456	WP_060972120.1	DUF3021 domain-containing protein	-
V6T26_RS09925 (V6T26_09910)	hexA	2110289..2112847 (-)	2559	WP_410541267.1	DNA mismatch repair protein MutS	Machinery gene
V6T26_RS09930 (V6T26_09915)	-	2112840..2113199 (-)	360	WP_410541268.1	YlbF family regulator	-
V6T26_RS09935 (V6T26_09920)	argR	2113199..2113627 (-)	429	WP_171963598.1	arginine repressor	-
V6T26_RS09940 (V6T26_09925)	argS	2113782..2115473 (+)	1692	WP_002889584.1	arginine--tRNA ligase	-
V6T26_RS09945 (V6T26_09930)	-	2116350..2116595 (-)	246	Protein_1918	adenylosuccinate lyase	-
V6T26_RS09950 (V6T26_09935)	-	2116635..2117483 (-)	849	WP_084915136.1	hypothetical protein	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95687.87 Da
• Isoelectric Point: 4.6413

>NTDB_id=853113 V6T26_RS09925 WP_410541267.1 2110289..2112847(-) (hexA) [Streptococcus salivarius strain KSS11]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKVESRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQATITERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQYLAKAIATVDVLQSLAVVAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNSLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGDTVTIQPQEKVSPQ
EKSATETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=853113 V6T26_RS09925 WP_410541267.1 2110289..2112847(-) (hexA) [Streptococcus salivarius strain KSS11]
ATGGCTAAGGAAAAGATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTGTT
TCGGATGGGGGATTTTTACGAATTATTTTACGATGATGCCGTTAAGGCTGCTCAAATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAACGCAGATAATCCCATTCCTATGGCAGGTGTTCCTTATCATTCGGCTCAAGCCTATATTGATGTCTTGGTT
GAGATGGGCTACAAAGTAGCCATTGCTGAGCAGATGGAGGACCCTAAACAGGCTGTTGGCGTGGTTAAGCGTGAGGTAGT
TCAGGTTATCACGCCAGGGACAGTGGTTGACAGCTCTAAACCTGATAATGCCAACAATTTCTTAGTAGCCATTGACAAGG
TTGAAAGTCGATTCGGCCTGGCCTATATGGATGTATCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTTAGTTCA
GTTTGCAGTGAAATTCAGAATCTTAAGGCACGTGAAGTAGTCGTTGGGTATGATTTACCTGAAGCTGATGAACAAGTTTT
GGTCAAGCAACTCAACCTGCTTCTCTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGTTTGACAG
ATTTGGAAAGCAGTGTGGCGGGTAAACTTCTCCAGTATGTTCATCGTACTCAGATGCGAGAGCTCAGTCATTTACAAAAG
GCTCAGCACTATGAGATTAAAGATTACTTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTGGAAAATGCTAG
GACGGGCAAGAAACACGGATCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTT
GGATTGATCGTCCTTTAGTGAATCAAGCCACTATCACCGAGCGTCAGAATATCATCCAAGTTTTCTTGGACAATTTCTTT
GAGCGTAGTGACTTGACTGAGAGTCTAAAAGGTGTTTACGATATTGAGCGCCTGGCCAGTCGTGTTTCCTTTGGCAAGGC
TAATCCAAAAGATTTGATTCAGCTAGGTCATACTTTGGCTCAAGTACCGGTCATTAAGGCGATTTTGGAGTCTTTTAATG
ATGAGGCCTTGTCACGTCTTTTACAAGAGTTAGATGCTCTGCCAGAATTAGAGAGTTTGATTCGGTCGGCTATTGATCCT
GATGCCCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGTGAGGGAACCTCATGGATCGCAGATATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAGATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGCTTTGGAACTGCTGAGTTGGCTAAGATAGAAGGTGAAATGCTTGAGGCGCGTGAAAAATC
ATCAACGCTGGAATATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATATTTGGCTA
AGGCTATTGCGACAGTCGATGTGCTTCAGAGTCTAGCTGTTGTAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAAT
GATGAGCATCGTATTGTTATTGATCAAGGCCGTCATGCAGTGGTTGAGAAGGTTATGGGCGTTCAAGAATACATTCCAAA
CACCATTACCTTTGACAGTCAGACCAATATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCCACCTATATGCGTC
AGTTAGCCTTGTCAGTAGTTATGGCTCAGATGGGGTCTTACGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGATGCT
ATCTATACACGTATTGGTGCTGCAGATGATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCA
GGCCATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCTACCTATGATGGTATGG
CCTTAGCTCAGTCTATTATTGAGTTTATTCATGACAAGGTGGGGGCTAAGACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAACAGTTTGACACACCTTGTAAACGTTCATGTGGCGACACTTGAAAAGGACGGTGAAGTGACTTTCCT
TCACAAGATTGTCGATGGACCAGCCGACAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAACTTGAGGGCGATACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAA
GAGAAATCTGCCACTGAAACGCATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGA
GTTGCGTGATTTAGATATTTACAACATGACACCTATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.296	100	0.743
mutS	Pseudomonas stutzeri strain ATCC 17587	36.301	100	0.369