Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   QYR57_RS07265 Genome accession   NZ_CP129327
Coordinates   1475355..1476041 (-) Length   228 a.a.
NCBI ID   WP_003101668.1    Uniprot ID   -
Organism   Streptococcus iniae strain Si 4-21     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1470355..1481041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYR57_RS07245 (QYR57_07250) dnaI 1471150..1472052 (-) 903 WP_367561465.1 primosomal protein DnaI -
  QYR57_RS07250 (QYR57_07255) - 1472053..1473241 (-) 1189 Protein_1408 helicase loader -
  QYR57_RS07255 (QYR57_07260) nrdR 1473225..1473719 (-) 495 WP_003101666.1 transcriptional regulator NrdR -
  QYR57_RS07260 (QYR57_07265) - 1473865..1475352 (-) 1488 WP_037584827.1 HAMP domain-containing histidine kinase -
  QYR57_RS07265 (QYR57_07270) covR 1475355..1476041 (-) 687 WP_003101668.1 two-component system response regulator CovR Regulator
  QYR57_RS07270 (QYR57_07275) - 1476270..1476803 (-) 534 WP_003101669.1 DUF177 domain-containing protein -
  QYR57_RS07275 (QYR57_07280) htpX 1476991..1477887 (-) 897 WP_367561466.1 zinc metalloprotease HtpX -
  QYR57_RS07280 (QYR57_07285) - 1477926..1478483 (-) 558 WP_367561467.1 LemA family protein -
  QYR57_RS07285 (QYR57_07290) rsmG 1478628..1479344 (+) 717 WP_003101672.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  QYR57_RS07290 (QYR57_07295) ktrB 1479436..1480797 (+) 1362 WP_017794720.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26670.62 Da        Isoelectric Point: 4.6541

>NTDB_id=852224 QYR57_RS07265 WP_003101668.1 1475355..1476041(-) (covR) [Streptococcus iniae strain Si 4-21]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEVNGREGLDTALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKSPNQGIYRDLVLNPQNRSVNRGDEEISLTKREY
DLLNILMSNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMQGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=852224 QYR57_RS07265 WP_003101668.1 1475355..1476041(-) (covR) [Streptococcus iniae strain Si 4-21]
ATGACAAAAAAAATTCTAATTGTTGAAGATGAAAAAAATCTTGCAAGGTTTGTTTCATTAGAATTGCAACACGAAGGTTA
CGAAGTAACTGTAGAAGTGAATGGTCGTGAAGGACTTGACACAGCGCTTGAAAAAGATTTTGATTTAATCTTGCTTGATT
TGATGTTACCTGAAATGGATGGTTTTGAAGTGACCCGTCGTCTTCAAACTGAAAAAACAACCTACATTATGATGATGACA
GCACGCGATTCTATCATGGACGTGGTTGCTGGTTTGGATCGTGGTGCAGATGATTATATTGTTAAGCCATTTGCTATTGA
AGAATTATTGGCACGTATTCGTGCAATTTTCCGTCGTCAAGATATTGAAACTGAGAAAAAATCTCCTAATCAAGGTATTT
ACCGTGATTTAGTCTTAAATCCACAAAACCGTTCTGTAAACCGTGGAGATGAAGAAATTTCATTGACAAAACGCGAATAT
GATTTGTTAAACATTTTAATGAGCAATATGAATCGTGTCATGACGCGTGAAGAGTTGCTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAACGTTGTTGACGTGTATATTCGTTACCTACGTGGAAAAATCGATATGCAAGGACGTGAGTCCT
ATATTCAAACTGTTCGTGGAATGGGATATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.52

99.561

0.662
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.434