Detailed information NTG0852219

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: QYR57_RS06255
• Genome accession: NZ_CP129327
• Coordinates: 1285505..1286230 (-)
• Length: 241 a.a.
• NCBI ID: WP_003101290.1
• Uniprot ID: A0A3L8GIX6
• Organism: Streptococcus iniae strain Si 4-21
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1280505..1291230

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYR57_RS06230 (QYR57_06235)	-	1281010..1281621 (-)	612	WP_367561381.1	phosphate ABC transporter ATP-binding protein	-
QYR57_RS06235 (QYR57_06240)	pstA	1281624..1282440 (-)	817	Protein_1205	phosphate ABC transporter permease PstA	-
QYR57_RS06240 (QYR57_06245)	pstC	1282433..1283296 (-)	864	WP_367561382.1	phosphate ABC transporter permease subunit PstC	-
QYR57_RS06245 (QYR57_06250)	-	1283359..1284039 (-)	681	WP_016356077.1	substrate-binding domain-containing protein	-
QYR57_RS06250 (QYR57_06255)	pnpS	1284193..1285521 (-)	1329	WP_003101288.1	two-component system histidine kinase PnpS	-
QYR57_RS06255 (QYR57_06260)	vicR	1285505..1286230 (-)	726	WP_003101290.1	response regulator transcription factor	Regulator
QYR57_RS06260 (QYR57_06265)	-	1286326..1286709 (-)	384	WP_003101292.1	VOC family protein	-
QYR57_RS06265 (QYR57_06270)	-	1286902..1287045 (+)	144	WP_003101294.1	SPJ_0845 family protein	-
QYR57_RS06270 (QYR57_06275)	-	1287045..1287950 (+)	906	WP_003101296.1	permease	-
QYR57_RS06275 (QYR57_06280)	-	1287947..1288762 (+)	816	WP_367561383.1	TIGR03943 family putative permease subunit	-
QYR57_RS06280 (QYR57_06285)	-	1288834..1289460 (-)	627	WP_003101299.1	NAD(P)-dependent oxidoreductase	-
QYR57_RS06285 (QYR57_06290)	-	1289747..1291123 (-)	1377	WP_367561384.1	PTS transporter subunit EIIC	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 28088.34 Da
• Isoelectric Point: 5.1365

>NTDB_id=852219 QYR57_RS06255 WP_003101290.1 1285505..1286230(-) (vicR) [Streptococcus iniae strain Si 4-21]
MKKTVLLVDDEEHILRLLDYHLSKEGFSIDTATDGRSALKLAETESYDFILLDIMLPQLDGIEVCKRIRAKNSKTPIMMV
SAKGEEFDKVLALELGADDYMTKPFSPRELLARVKAILRRTGKDDSQQEEFGFADQRFLVNDLVIYPERNEVYKEQDLIS
LTPKEYELLMYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDDPKNPEMIKTIRGYGYQFKEMKDATK
S

Nucleotide

• Length: 726 bp

>NTDB_id=852219 QYR57_RS06255 WP_003101290.1 1285505..1286230(-) (vicR) [Streptococcus iniae strain Si 4-21]
ATGAAAAAGACAGTTTTATTAGTAGACGACGAAGAGCACATCTTACGTTTATTAGACTATCATCTCAGCAAGGAAGGCTT
TAGTATTGACACAGCAACAGATGGCAGATCAGCACTAAAATTAGCTGAAACAGAAAGTTATGACTTCATTTTGTTAGACA
TCATGTTGCCCCAATTGGACGGTATTGAGGTCTGTAAACGTATCAGAGCTAAAAATAGTAAGACCCCTATTATGATGGTA
TCAGCTAAAGGGGAAGAATTTGACAAGGTCCTAGCCTTAGAACTAGGAGCTGATGATTACATGACAAAACCCTTTAGTCC
AAGGGAATTGCTGGCGCGTGTAAAAGCTATTTTAAGACGAACAGGAAAAGACGACAGCCAACAAGAAGAGTTTGGCTTCG
CTGACCAGCGATTCTTGGTCAATGACTTGGTCATTTACCCTGAAAGAAATGAAGTTTACAAAGAGCAAGACTTGATTTCC
TTAACCCCAAAAGAGTATGAACTGTTAATGTATTTAGTCAAACATCCCAATATGACCTTAACAAGAGAACGACTTTTAGA
ACGGATTTGGGGGTATGACTTTGGCCAAGAAACACGTTTAGTAGATGTTCATATTGGAAAATTAAGAGACAAAATTGAAG
ATGATCCTAAAAATCCAGAGATGATTAAAACAATCAGGGGCTATGGCTATCAGTTTAAGGAGATGAAGGATGCTACAAAA
TCTTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-115)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (159-232)

3D structure

• AlphaFold DB: A0A3L8GIX6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	51.293	96.266	0.494
micA	Streptococcus pneumoniae Cp1015	48.918	95.851	0.469
covR	Lactococcus lactis subsp. lactis strain DGCC12653	42.194	98.34	0.415
covR	Streptococcus salivarius strain HSISS4	39.316	97.095	0.382