Detailed information NTG0851299

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LLNCDO702_RS09360
• Genome accession: NZ_CP129159
• Coordinates: 1898412..1900622 (-)
• Length: 736 a.a.
• NCBI ID: WP_081144329.1
• Uniprot ID: A0A1V0NHP3
• Organism: Lactococcus lactis subsp. lactis strain NCDO702
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1893412..1905622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLNCDO702_RS09330 (LLNCDO702_09315)	atpA	1893455..1894957 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
LLNCDO702_RS09335 (LLNCDO702_09320)	-	1895144..1895671 (-)	528	WP_004255262.1	F0F1 ATP synthase subunit delta	-
LLNCDO702_RS09340 (LLNCDO702_09325)	atpF	1895673..1896179 (-)	507	WP_004255258.1	F0F1 ATP synthase subunit B	-
LLNCDO702_RS09345 (LLNCDO702_09330)	atpB	1896194..1896907 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
LLNCDO702_RS09350 (LLNCDO702_09335)	-	1896952..1897167 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
LLNCDO702_RS09355 (LLNCDO702_09340)	-	1897351..1898127 (-)	777	WP_004255244.1	alpha/beta hydrolase family protein	-
LLNCDO702_RS09360 (LLNCDO702_09345)	comEC	1898412..1900622 (-)	2211	WP_081144329.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LLNCDO702_RS09365 (LLNCDO702_09350)	comEA	1900603..1901250 (-)	648	WP_004255240.1	ComEA family DNA-binding protein	Machinery gene
LLNCDO702_RS09370 (LLNCDO702_09355)	-	1901310..1902671 (-)	1362	WP_004255239.1	ABC transporter permease	-
LLNCDO702_RS09375 (LLNCDO702_09360)	-	1902668..1903600 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LLNCDO702_RS09380 (LLNCDO702_09365)	-	1903705..1904103 (-)	399	WP_004255236.1	hypothetical protein	-
LLNCDO702_RS09385 (LLNCDO702_09370)	-	1904207..1904770 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84511.27 Da
• Isoelectric Point: 9.7831

>NTDB_id=851299 LLNCDO702_RS09360 WP_081144329.1 1898412..1900622(-) (comEC) [Lactococcus lactis subsp. lactis strain NCDO702]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWPQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKISELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKFDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=851299 LLNCDO702_RS09360 WP_081144329.1 1898412..1900622(-) (comEC) [Lactococcus lactis subsp. lactis strain NCDO702]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGTCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGCCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAAATTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGGGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAATTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Competence protein (Competence) (206-446)

3D structure

• AlphaFold DB: A0A1V0NHP3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.766	100	0.768
comEC/celB	Streptococcus mitis SK321	44.34	100	0.447
comEC/celB	Streptococcus mitis NCTC 12261	44.205	100	0.446
comEC/celB	Streptococcus pneumoniae TIGR4	43.472	100	0.439
comEC/celB	Streptococcus pneumoniae Rx1	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae D39	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae R6	43.069	100	0.435