Detailed information NTG0848404

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: QTV59_RS04230
• Genome accession: NZ_CP128526
• Coordinates: 812571..813767 (+)
• Length: 398 a.a.
• NCBI ID: WP_006248403.1
• Uniprot ID: A0A249A0I8
• Organism: Mannheimia haemolytica strain 171117
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 807571..818767

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTV59_RS04200	proB	807967..809051 (-)	1085	Protein_804	glutamate 5-kinase	-
QTV59_RS04205	folA	809163..809657 (+)	495	WP_006248397.1	type 3 dihydrofolate reductase	-
QTV59_RS04210	-	809777..810007 (+)	231	WP_006248398.1	YgjV family protein	-
QTV59_RS04215	radA	810062..811441 (-)	1380	WP_006248399.1	DNA repair protein RadA	-
QTV59_RS04220	pilA	811622..812101 (+)	480	WP_006248401.1	prepilin peptidase-dependent pilin	Machinery gene
QTV59_RS04225	-	812122..812565 (+)	444	Protein_809	pilus assembly protein PilB	-
QTV59_RS04230	pilC	812571..813767 (+)	1197	WP_006248403.1	type II secretion system F family protein	Machinery gene
QTV59_RS04235	-	813770..814426 (+)	657	WP_006248404.1	prepilin peptidase	-
QTV59_RS04240	coaE	814462..815097 (+)	636	WP_006248405.1	dephospho-CoA kinase	-
QTV59_RS04245	yacG	815079..815264 (+)	186	WP_006248406.1	DNA gyrase inhibitor YacG	-
QTV59_RS04250	holA	815265..816290 (-)	1026	WP_006253426.1	DNA polymerase III subunit delta	-
QTV59_RS04255	lptE	816333..816821 (-)	489	WP_006248408.1	LPS assembly lipoprotein LptE	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45186.75 Da
• Isoelectric Point: 9.4698

>NTDB_id=848404 QTV59_RS04230 WP_006248403.1 812571..813767(+) (pilC) [Mannheimia haemolytica strain 171117]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLFFAKKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide

• Length: 1197 bp

>NTDB_id=848404 QTV59_RS04230 WP_006248403.1 812571..813767(+) (pilC) [Mannheimia haemolytica strain 171117]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGTTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTTTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTTTTTGCAAAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGCGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (64-186)

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

3D structure

• AlphaFold DB: A0A249A0I8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	54	100	0.543
pilC	Haemophilus influenzae Rd KW20	42.145	100	0.425
pilC	Haemophilus influenzae 86-028NP	41.147	100	0.415