Detailed information NTG0848386

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: QTV52_RS09255
• Genome accession: NZ_CP128525
• Coordinates: 1750720..1751916 (-)
• Length: 398 a.a.
• NCBI ID: WP_006248403.1
• Uniprot ID: A0A249A0I8
• Organism: Mannheimia haemolytica strain 171555
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1745720..1756916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTV52_RS09230	lptE	1747666..1748154 (+)	489	WP_006248408.1	LPS assembly lipoprotein LptE	-
QTV52_RS09235	holA	1748197..1749222 (+)	1026	WP_006253426.1	DNA polymerase III subunit delta	-
QTV52_RS09240	yacG	1749223..1749408 (-)	186	WP_006248406.1	DNA gyrase inhibitor YacG	-
QTV52_RS09245	coaE	1749390..1750025 (-)	636	WP_006248405.1	dephospho-CoA kinase	-
QTV52_RS09250	-	1750061..1750717 (-)	657	WP_006248404.1	prepilin peptidase	-
QTV52_RS09255	pilC	1750720..1751916 (-)	1197	WP_006248403.1	type II secretion system F family protein	Machinery gene
QTV52_RS09260	-	1751922..1752365 (-)	444	Protein_1786	pilus assembly protein PilB	-
QTV52_RS09265	pilA	1752386..1752865 (-)	480	WP_006248401.1	prepilin peptidase-dependent pilin	Machinery gene
QTV52_RS09270	radA	1753046..1754425 (+)	1380	WP_006248399.1	DNA repair protein RadA	-
QTV52_RS09275	-	1754480..1754710 (-)	231	WP_006248398.1	YgjV family protein	-
QTV52_RS09280	folA	1754830..1755324 (-)	495	WP_006248397.1	type 3 dihydrofolate reductase	-
QTV52_RS09285	proB	1755436..1756520 (+)	1085	Protein_1791	glutamate 5-kinase	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45186.75 Da
• Isoelectric Point: 9.4698

>NTDB_id=848386 QTV52_RS09255 WP_006248403.1 1750720..1751916(-) (pilC) [Mannheimia haemolytica strain 171555]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLFFAKKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide

• Length: 1197 bp

>NTDB_id=848386 QTV52_RS09255 WP_006248403.1 1750720..1751916(-) (pilC) [Mannheimia haemolytica strain 171555]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGTTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTTTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTTTTTGCAAAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGCGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (64-186)

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

3D structure

• AlphaFold DB: A0A249A0I8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	54	100	0.543
pilC	Haemophilus influenzae Rd KW20	42.145	100	0.425
pilC	Haemophilus influenzae 86-028NP	41.147	100	0.415