Detailed information NTG0848365

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: QTV56_RS07820
• Genome accession: NZ_CP128524
• Coordinates: 1533710..1534906 (+)
• Length: 398 a.a.
• NCBI ID: WP_006248403.1
• Uniprot ID: A0A249A0I8
• Organism: Mannheimia haemolytica strain 181789
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1528710..1539906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTV56_RS07790	proB	1529106..1530190 (-)	1085	Protein_1501	glutamate 5-kinase	-
QTV56_RS07795	folA	1530302..1530796 (+)	495	WP_006248397.1	type 3 dihydrofolate reductase	-
QTV56_RS07800	-	1530916..1531146 (+)	231	WP_006248398.1	YgjV family protein	-
QTV56_RS07805	radA	1531201..1532580 (-)	1380	WP_006248399.1	DNA repair protein RadA	-
QTV56_RS07810	pilA	1532761..1533240 (+)	480	WP_006248401.1	prepilin peptidase-dependent pilin	Machinery gene
QTV56_RS07815	-	1533261..1533704 (+)	444	Protein_1506	pilus assembly protein PilB	-
QTV56_RS07820	pilC	1533710..1534906 (+)	1197	WP_006248403.1	type II secretion system F family protein	Machinery gene
QTV56_RS07825	-	1534909..1535565 (+)	657	WP_006248404.1	prepilin peptidase	-
QTV56_RS07830	coaE	1535601..1536236 (+)	636	WP_006248405.1	dephospho-CoA kinase	-
QTV56_RS07835	yacG	1536218..1536403 (+)	186	WP_006248406.1	DNA gyrase inhibitor YacG	-
QTV56_RS07840	holA	1536404..1537429 (-)	1026	WP_006253426.1	DNA polymerase III subunit delta	-
QTV56_RS07845	lptE	1537472..1537960 (-)	489	WP_289332991.1	LPS assembly lipoprotein LptE	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45186.75 Da
• Isoelectric Point: 9.4698

>NTDB_id=848365 QTV56_RS07820 WP_006248403.1 1533710..1534906(+) (pilC) [Mannheimia haemolytica strain 181789]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLFFAKKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide

• Length: 1197 bp

>NTDB_id=848365 QTV56_RS07820 WP_006248403.1 1533710..1534906(+) (pilC) [Mannheimia haemolytica strain 181789]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGTTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTTTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTTTTTGCAAAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGCGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (64-186)

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

3D structure

• AlphaFold DB: A0A249A0I8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	54	100	0.543
pilC	Haemophilus influenzae Rd KW20	42.145	100	0.425
pilC	Haemophilus influenzae 86-028NP	41.147	100	0.415