Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   COW1_RS16025 Genome accession   NZ_AP024239
Coordinates   3374562..3375911 (-) Length   449 a.a.
NCBI ID   WP_201344759.1    Uniprot ID   A0A7R7GQB4
Organism   Thiohalobacter sp. COW1     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 3369562..3380911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COW1_RS16005 - 3369754..3370893 (-) 1140 WP_201344751.1 glycosyltransferase family 4 protein -
  COW1_RS16010 (TspCOW1_31740) - 3370915..3371760 (-) 846 WP_201344753.1 glycosyltransferase family 2 protein -
  COW1_RS16015 (TspCOW1_31750) - 3371783..3373756 (-) 1974 WP_201344755.1 hypothetical protein -
  COW1_RS16020 (TspCOW1_31760) pilA2 3373826..3374251 (-) 426 WP_201344757.1 pilin Machinery gene
  COW1_RS16025 (TspCOW1_31770) pilR 3374562..3375911 (-) 1350 WP_201344759.1 sigma-54 dependent transcriptional regulator Regulator
  COW1_RS16030 (TspCOW1_31780) - 3376190..3377812 (-) 1623 WP_201344761.1 ATP-binding protein -
  COW1_RS16035 - 3377809..3378048 (-) 240 WP_201344763.1 PP0621 family protein -
  COW1_RS16040 (TspCOW1_31800) sucC 3378276..3379460 (+) 1185 WP_201344765.1 ADP-forming succinate--CoA ligase subunit beta -
  COW1_RS16045 (TspCOW1_31810) sucD 3379553..3380422 (+) 870 WP_201344767.1 succinate--CoA ligase subunit alpha -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49265.24 Da        Isoelectric Point: 5.2706

>NTDB_id=84258 COW1_RS16025 WP_201344759.1 3374562..3375911(-) (pilR) [Thiohalobacter sp. COW1]
MPRYRALVVDDEPDILELIEITLGRMGIDTTAAADLAAARAQLGNGERFDLCLTDMRLPDGSGLDLVAEIQAGRPDLPVA
VITAYGNMDTAVQALKAGAFDFVSKPVDLQVLRNLVGTALKLSDTRSFPARDRRSRDELIGDSAPMQRIRALIAKLARSQ
APVYISGESGTGKELVARLIHDKGPRAEQPFIAVNCGAIPAELMESEFFGHKKGSFTGAAGDKEGLFQAASGGTLFLDEV
AELPLHMQVKLLRAIQEKAVRPVGEQREAPVDVRVLTATHKNLEQLVRDGHFRQDLYFRINVIELKVPPLRERREDIPRL
VEHLLNKLGHDARHRLSDTAVQALQAYDFAGNVRELENILERAVTMAEGEVIEVEDLHLQTNTASEQPTTAGNPPPPGSV
PLEDYLGEIEKQAILDALEQTHQNKTAAAELLGLSFRALRYRLKKLGLD

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=84258 COW1_RS16025 WP_201344759.1 3374562..3375911(-) (pilR) [Thiohalobacter sp. COW1]
ATGCCCCGCTACCGCGCACTCGTTGTCGATGACGAACCCGACATCCTCGAGCTGATCGAGATCACGCTCGGGCGCATGGG
CATCGACACCACCGCCGCCGCCGATCTGGCCGCGGCGCGCGCGCAACTCGGCAACGGTGAACGCTTCGACCTGTGCCTGA
CCGACATGCGCCTGCCCGACGGCTCAGGCCTGGACCTGGTCGCCGAGATCCAGGCCGGCCGCCCCGACCTGCCGGTGGCC
GTGATCACCGCCTACGGCAACATGGACACCGCTGTGCAGGCGCTCAAGGCCGGTGCCTTCGACTTCGTCTCCAAGCCGGT
GGACCTGCAGGTGCTGCGCAACCTGGTGGGCACCGCACTGAAACTCTCCGATACCCGCAGCTTTCCCGCGCGCGACCGTC
GCTCCCGCGACGAACTGATCGGCGACTCTGCCCCCATGCAGCGCATCCGCGCCCTGATCGCCAAGCTGGCCCGCAGCCAG
GCGCCGGTCTACATCAGCGGCGAATCCGGCACCGGCAAAGAACTGGTCGCCCGGCTGATCCACGACAAGGGCCCGCGCGC
CGAACAGCCCTTCATCGCCGTGAACTGCGGCGCCATCCCGGCCGAGTTGATGGAAAGCGAGTTCTTCGGTCACAAAAAAG
GCAGCTTCACCGGCGCGGCCGGCGACAAGGAAGGGCTGTTCCAGGCTGCCAGCGGCGGCACCCTGTTCCTGGACGAGGTC
GCCGAACTGCCCCTGCACATGCAGGTCAAGCTGCTGCGCGCCATCCAGGAGAAGGCCGTGCGCCCGGTGGGCGAGCAGCG
CGAGGCGCCGGTGGATGTACGGGTGCTGACCGCCACCCACAAGAACCTGGAGCAGCTGGTGCGCGACGGCCACTTCCGCC
AGGACCTGTACTTCCGCATCAACGTGATCGAACTCAAGGTCCCGCCCCTGCGCGAGCGGCGCGAAGACATCCCCCGGCTG
GTCGAGCACCTGCTGAACAAGCTCGGCCACGACGCCCGGCACCGGCTGAGCGACACCGCAGTGCAGGCCCTGCAGGCCTA
CGACTTCGCCGGCAACGTGCGCGAGCTGGAAAACATCCTGGAACGCGCTGTCACCATGGCCGAAGGCGAGGTGATCGAGG
TCGAAGACCTGCACCTGCAGACGAACACGGCAAGCGAGCAACCGACCACGGCCGGTAATCCACCGCCGCCCGGCAGCGTC
CCGCTGGAGGACTACCTGGGCGAGATCGAGAAACAGGCGATACTGGATGCCCTGGAACAGACCCATCAGAACAAGACCGC
CGCCGCCGAACTGCTGGGCCTGAGTTTCCGCGCCCTGCGCTACCGCCTTAAGAAGCTGGGACTGGACTGA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(139-305)

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(406-446)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7R7GQB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

63.496

100

0.639
  pilR Acinetobacter baumannii strain A118

52.505

100

0.537
  luxO Vibrio cholerae strain A1552

37.892

99.332

0.376

Multiple sequence alignment