Detailed information
Bioinformatically predicted
Overview
| Name | comEC | Type | Machinery gene |
| Locus tag | JG741_RS11455 | Genome accession | NZ_AP024210 |
| Coordinates | 2240674..2241945 (+) | Length | 423 a.a. |
| NCBI ID | WP_324187043.1 | Uniprot ID | - |
| Organism | Lactococcus cremoris strain G3-2 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2203975..2283336 | 2240674..2241945 | within | 0 |
| IS/Tn | 2242528..2243418 | 2240674..2241945 | flank | 583 |
Gene organization within MGE regions
Location: 2203975..2283336
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JG741_RS11300 (LLG32_23270) | - | 2205449..2206987 (-) | 1539 | Protein_2236 | M13-type metalloendopeptidase | - |
| JG741_RS11305 (LLG32_23280) | - | 2207144..2207818 (-) | 675 | WP_015082761.1 | helix-turn-helix domain-containing protein | - |
| JG741_RS11310 (LLG32_23290) | - | 2208054..2208653 (+) | 600 | WP_011676808.1 | transcriptional regulator | - |
| JG741_RS11315 (LLG32_23300) | rpoB | 2208922..2212512 (+) | 3591 | WP_126354712.1 | DNA-directed RNA polymerase subunit beta | - |
| JG741_RS11320 (LLG32_23310) | rpoC | 2212620..2216243 (+) | 3624 | WP_164717651.1 | DNA-directed RNA polymerase subunit beta' | - |
| JG741_RS11325 (LLG32_23320) | - | 2216424..2217275 (+) | 852 | WP_308167263.1 | diacylglycerol/lipid kinase family protein | - |
| JG741_RS11330 (LLG32_23330) | - | 2217421..2218107 (+) | 687 | WP_014572148.1 | amino acid ABC transporter permease | - |
| JG741_RS11335 (LLG32_23340) | - | 2218107..2218841 (+) | 735 | WP_011676803.1 | amino acid ABC transporter ATP-binding protein | - |
| JG741_RS11340 (LLG32_23350) | mecA | 2218970..2219671 (+) | 702 | WP_011676802.1 | adaptor protein MecA | Regulator |
| JG741_RS11345 (LLG32_23360) | - | 2219674..2220999 (+) | 1326 | WP_126354714.1 | glycosyltransferase family 4 protein | - |
| JG741_RS11350 (LLG32_23370) | sufC | 2221175..2221945 (+) | 771 | WP_011676800.1 | Fe-S cluster assembly ATPase SufC | - |
| JG741_RS11355 (LLG32_23380) | sufD | 2222085..2223341 (+) | 1257 | WP_021165660.1 | Fe-S cluster assembly protein SufD | - |
| JG741_RS11360 (LLG32_23390) | - | 2223341..2224561 (+) | 1221 | WP_021213770.1 | cysteine desulfurase | - |
| JG741_RS11365 (LLG32_23400) | - | 2224563..2225045 (+) | 483 | WP_031286519.1 | hypothetical protein | - |
| JG741_RS11370 (LLG32_23410) | sufU | 2225179..2225637 (+) | 459 | WP_011676796.1 | Fe-S cluster assembly sulfur transfer protein SufU | - |
| JG741_RS11375 (LLG32_23420) | sufB | 2225733..2227145 (+) | 1413 | WP_004255207.1 | Fe-S cluster assembly protein SufB | - |
| JG741_RS11380 (LLG32_23430) | - | 2227492..2227782 (+) | 291 | WP_011676794.1 | WXG100 family type VII secretion target | - |
| JG741_RS11385 (LLG32_23440) | essA | 2227890..2228360 (+) | 471 | WP_011835707.1 | type VII secretion protein EssA | - |
| JG741_RS11390 (LLG32_23450) | - | 2228482..2228727 (+) | 246 | WP_021165657.1 | hypothetical protein | - |
| JG741_RS11395 (LLG32_23460) | esaA | 2228790..2230790 (+) | 2001 | WP_061777933.1 | type VII secretion protein EsaA | - |
| JG741_RS11400 (LLG32_23470) | - | 2230791..2231681 (-) | 891 | WP_206604081.1 | IS982-like element IS982B family transposase | - |
| JG741_RS11405 (LLG32_23480) | - | 2231882..2232451 (+) | 570 | WP_011676781.1 | biotin transporter BioY | - |
| JG741_RS11410 (LLG32_23490) | - | 2232457..2233428 (+) | 972 | WP_015082750.1 | biotin--[acetyl-CoA-carboxylase] ligase | - |
| JG741_RS11415 (LLG32_23500) | - | 2233449..2233751 (+) | 303 | WP_011676779.1 | CHY zinc finger protein | - |
| JG741_RS11420 (LLG32_23510) | tenA | 2233970..2234626 (+) | 657 | WP_011835701.1 | thiaminase II | - |
| JG741_RS11425 (LLG32_23520) | - | 2235014..2236192 (+) | 1179 | WP_011676777.1 | SLC13 family permease | - |
| JG741_RS11430 (LLG32_23530) | - | 2236365..2236925 (+) | 561 | WP_032950467.1 | GNAT family N-acetyltransferase | - |
| JG741_RS11440 (LLG32_23540) | - | 2237545..2238477 (+) | 933 | WP_014572202.1 | ABC transporter ATP-binding protein | - |
| JG741_RS11445 (LLG32_23550) | - | 2238474..2239835 (+) | 1362 | WP_061777936.1 | ABC transporter permease | - |
| JG741_RS11450 (LLG32_23560) | comEA | 2239966..2240448 (+) | 483 | WP_232035111.1 | SLBB domain-containing protein | Machinery gene |
| JG741_RS14450 | comEA | 2240445..2240546 (+) | 102 | WP_228764031.1 | ComEA family DNA-binding protein | Machinery gene |
| JG741_RS11455 (LLG32_23570) | comEC | 2240674..2241945 (+) | 1272 | WP_324187043.1 | ComEC/Rec2 family competence protein | Machinery gene |
| JG741_RS14455 (LLG32_23580) | comEC | 2241942..2242451 (+) | 510 | WP_232035112.1 | MBL fold metallo-hydrolase | Machinery gene |
| JG741_RS11460 (LLG32_23590) | - | 2242528..2243418 (+) | 891 | WP_206604078.1 | IS982-like element IS982B family transposase | - |
| JG741_RS11465 (LLG32_23600) | - | 2243439..2243744 (+) | 306 | Protein_2270 | ComEC/Rec2 family competence protein | - |
| JG741_RS11470 (LLG32_23610) | - | 2244028..2244804 (+) | 777 | WP_061778314.1 | alpha/beta hydrolase | - |
| JG741_RS11475 (LLG32_23620) | - | 2244987..2245202 (+) | 216 | WP_014572212.1 | F0F1 ATP synthase subunit C | - |
| JG741_RS11480 (LLG32_23630) | atpB | 2245249..2245962 (+) | 714 | WP_004255255.1 | F0F1 ATP synthase subunit A | - |
| JG741_RS11485 (LLG32_23640) | atpF | 2245977..2246483 (+) | 507 | WP_010906128.1 | F0F1 ATP synthase subunit B | - |
| JG741_RS11490 (LLG32_23650) | - | 2246485..2247012 (+) | 528 | WP_014572213.1 | F0F1 ATP synthase subunit delta | - |
| JG741_RS11495 (LLG32_23660) | atpA | 2247200..2248702 (+) | 1503 | WP_061778315.1 | F0F1 ATP synthase subunit alpha | - |
| JG741_RS11500 (LLG32_23670) | - | 2248718..2249587 (+) | 870 | WP_021165644.1 | F0F1 ATP synthase subunit gamma | - |
| JG741_RS11505 (LLG32_23680) | atpD | 2249759..2251168 (+) | 1410 | WP_021165643.1 | F0F1 ATP synthase subunit beta | - |
| JG741_RS11510 (LLG32_23690) | - | 2251353..2251778 (+) | 426 | WP_011676764.1 | F0F1 ATP synthase subunit epsilon | - |
| JG741_RS11515 (LLG32_23700) | - | 2251894..2252541 (+) | 648 | WP_014572215.1 | hypothetical protein | - |
| JG741_RS11520 (LLG32_23710) | - | 2252542..2253069 (+) | 528 | WP_232035113.1 | hypothetical protein | - |
| JG741_RS14460 (LLG32_23720) | - | 2253082..2253480 (+) | 399 | WP_232035114.1 | hypothetical protein | - |
| JG741_RS11525 (LLG32_23740) | - | 2253517..2254628 (+) | 1112 | WP_101944661.1 | IS3-like element IS981 family transposase | - |
| JG741_RS11530 (LLG32_23750) | - | 2254685..2254933 (+) | 249 | WP_061777790.1 | hypothetical protein | - |
| JG741_RS11535 (LLG32_23760) | - | 2255056..2255589 (+) | 534 | WP_126354720.1 | hypothetical protein | - |
| JG741_RS11540 (LLG32_23770) | - | 2255646..2256389 (-) | 744 | WP_011676756.1 | amino acid ABC transporter ATP-binding protein | - |
| JG741_RS11545 (LLG32_23780) | - | 2256412..2258556 (-) | 2145 | WP_011676755.1 | amino acid ABC transporter substrate-binding protein/permease | - |
| JG741_RS11550 (LLG32_23790) | - | 2258925..2259581 (+) | 657 | WP_014572220.1 | VTT domain-containing protein | - |
| JG741_RS11555 (LLG32_23800) | - | 2259759..2260619 (+) | 861 | WP_021165626.1 | shikimate dehydrogenase | - |
| JG741_RS11560 (LLG32_23810) | aroB | 2260616..2261686 (+) | 1071 | WP_061777788.1 | 3-dehydroquinate synthase | - |
| JG741_RS11565 (LLG32_23820) | - | 2261800..2262723 (+) | 924 | WP_061777787.1 | DMT family transporter | - |
| JG741_RS11570 (LLG32_23830) | - | 2263095..2263694 (+) | 600 | WP_014572223.1 | DUF1054 domain-containing protein | - |
| JG741_RS11575 (LLG32_23840) | - | 2263699..2264295 (+) | 597 | WP_021165625.1 | HAD-IA family hydrolase | - |
| JG741_RS11580 (LLG32_23850) | aroC | 2264326..2265492 (+) | 1167 | WP_011676748.1 | chorismate synthase | - |
| JG741_RS11585 (LLG32_23860) | - | 2265614..2265970 (+) | 357 | WP_061777786.1 | YxeA family protein | - |
| JG741_RS11590 (LLG32_23880) | - | 2266165..2266944 (+) | 780 | WP_021165624.1 | ABC transporter ATP-binding protein | - |
| JG741_RS11595 (LLG32_23890) | - | 2266937..2268946 (+) | 2010 | WP_032950486.1 | ABC transporter permease | - |
| JG741_RS11600 (LLG32_23900) | - | 2268967..2269914 (-) | 948 | WP_003130410.1 | IS30 family transposase | - |
| JG741_RS11605 (LLG32_23910) | - | 2270213..2271277 (+) | 1065 | WP_011676743.1 | VanZ family protein | - |
| JG741_RS11610 (LLG32_23920) | - | 2271280..2271951 (+) | 672 | WP_021165622.1 | response regulator transcription factor | - |
| JG741_RS14690 | - | 2271938..2272812 (+) | 875 | Protein_2301 | sensor histidine kinase | - |
| JG741_RS11620 (LLG32_23950) | - | 2272816..2273880 (+) | 1065 | WP_011676740.1 | prephenate dehydrogenase | - |
| JG741_RS11625 (LLG32_23960) | aroA | 2274001..2275293 (+) | 1293 | WP_126354722.1 | 3-phosphoshikimate 1-carboxyvinyltransferase | - |
| JG741_RS11630 (LLG32_23970) | - | 2275317..2275805 (+) | 489 | WP_011676738.1 | shikimate kinase | - |
| JG741_RS11635 (LLG32_23980) | pheA | 2275807..2276646 (+) | 840 | WP_011676737.1 | prephenate dehydratase | - |
| JG741_RS11640 (LLG32_23990) | - | 2276649..2277242 (+) | 594 | WP_061777784.1 | histidine phosphatase family protein | - |
| JG741_RS11645 (LLG32_24000) | - | 2277239..2279740 (+) | 2502 | WP_126354724.1 | ATP-dependent RecD-like DNA helicase | - |
| JG741_RS11650 (LLG32_24010) | rpsT | 2279834..2280067 (-) | 234 | WP_011676734.1 | 30S ribosomal protein S20 | - |
| JG741_RS11655 (LLG32_24020) | - | 2280397..2280909 (+) | 513 | WP_061777782.1 | HD domain-containing protein | - |
| JG741_RS11660 (LLG32_24030) | - | 2281089..2282003 (+) | 915 | WP_011676732.1 | diacylglycerol/lipid kinase family protein | - |
| JG741_RS11665 (LLG32_24040) | - | 2282125..2283336 (-) | 1212 | WP_126354726.1 | tyrosine-type recombinase/integrase | - |
Sequence
Protein
Download Length: 423 a.a. Molecular weight: 49018.13 Da Isoelectric Point: 9.7194
>NTDB_id=84108 JG741_RS11455 WP_324187043.1 2240674..2241945(+) (comEC) [Lactococcus cremoris strain G3-2]
MIPILIVFAVFFLLINSLSIRDNENQPKNLSKIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKGFYQNLSQNC
QLSFTGNLEIPETQRNFNGFDDQKYLTSQNIYRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFG
FLSKDFNQMSDIYSSLGIIHLFALSGMQVNFFIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNI
RLTSLDNIAVTTLVLMLISPKFLLTTGGQLTLFYAFVISMLNHPFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLS
ILLTIIFGFLFDFMLLPLLLCCFLISFLGFSLNLNYIFQILEWLVYKVDLPLHYPFVLGKPSSLELIILFVLIGLFVDSF
SHKKRRFFLIGFIFLFFSSLKIQ
MIPILIVFAVFFLLINSLSIRDNENQPKNLSKIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKGFYQNLSQNC
QLSFTGNLEIPETQRNFNGFDDQKYLTSQNIYRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFG
FLSKDFNQMSDIYSSLGIIHLFALSGMQVNFFIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNI
RLTSLDNIAVTTLVLMLISPKFLLTTGGQLTLFYAFVISMLNHPFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLS
ILLTIIFGFLFDFMLLPLLLCCFLISFLGFSLNLNYIFQILEWLVYKVDLPLHYPFVLGKPSSLELIILFVLIGLFVDSF
SHKKRRFFLIGFIFLFFSSLKIQ
Nucleotide
Download Length: 1272 bp
>NTDB_id=84108 JG741_RS11455 WP_324187043.1 2240674..2241945(+) (comEC) [Lactococcus cremoris strain G3-2]
ATGATTCCGATATTAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACC
AAAAAATCTCTCAAAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGA
ATGGACAAAAATATCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGGGTTTTATCAGAACTTAAGTCAAAATTGT
CAGTTAAGTTTCACAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAAC
TAGTCAAAATATCTATCGACAGATTACCATCCAACAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTT
TAAGGCGAAAGGCAATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACGGGTTTGCTTTTTGGC
TTTTTAAGTAAGGATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAAT
GCAAGTAAATTTTTTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTC
AAATTCCATTTTCTATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATT
CGTCTGACTTCTTTGGATAATATCGCAGTTACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACGACTGG
TGGTCAGCTTACCTTGTTTTATGCTTTTGTCATTTCGATGCTTAATCATCCTTTTTCTAATTTAAATGGATTGAAAAAAG
TGCTGACAGAATCATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCA
ATATTATTAACAATTATATTTGGTTTTCTTTTTGATTTTATGTTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATT
TTTGGGATTTTCGCTCAATTTAAATTATATTTTTCAAATTCTAGAATGGCTAGTTTATAAAGTTGATTTACCCTTACATT
ACCCCTTTGTTTTGGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTT
TCTCATAAAAAAAGGAGATTTTTTTTAATTGGATTTATATTTTTATTTTTTTCATCACTAAAAATCCAATGA
ATGATTCCGATATTAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACC
AAAAAATCTCTCAAAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGA
ATGGACAAAAATATCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGGGTTTTATCAGAACTTAAGTCAAAATTGT
CAGTTAAGTTTCACAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAAC
TAGTCAAAATATCTATCGACAGATTACCATCCAACAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTT
TAAGGCGAAAGGCAATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACGGGTTTGCTTTTTGGC
TTTTTAAGTAAGGATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAAT
GCAAGTAAATTTTTTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTC
AAATTCCATTTTCTATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATT
CGTCTGACTTCTTTGGATAATATCGCAGTTACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACGACTGG
TGGTCAGCTTACCTTGTTTTATGCTTTTGTCATTTCGATGCTTAATCATCCTTTTTCTAATTTAAATGGATTGAAAAAAG
TGCTGACAGAATCATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCA
ATATTATTAACAATTATATTTGGTTTTCTTTTTGATTTTATGTTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATT
TTTGGGATTTTCGCTCAATTTAAATTATATTTTTCAAATTCTAGAATGGCTAGTTTATAAAGTTGATTTACCCTTACATT
ACCCCTTTGTTTTGGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTT
TCTCATAAAAAAAGGAGATTTTTTTTAATTGGATTTATATTTTTATTTTTTTCATCACTAAAAATCCAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comEC | Lactococcus lactis subsp. cremoris KW2 |
97.122 |
98.582 |
0.957 |
| comEC/celB | Streptococcus mitis SK321 |
46.512 |
91.489 |
0.426 |
| comEC/celB | Streptococcus mitis NCTC 12261 |
45.995 |
91.489 |
0.421 |
| comEC/celB | Streptococcus pneumoniae TIGR4 |
45.995 |
91.489 |
0.421 |
| comEC/celB | Streptococcus pneumoniae Rx1 |
45.22 |
91.489 |
0.414 |
| comEC/celB | Streptococcus pneumoniae D39 |
45.22 |
91.489 |
0.414 |
| comEC/celB | Streptococcus pneumoniae R6 |
45.22 |
91.489 |
0.414 |