Detailed information NTG0840465

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: VKP53_RS00350
• Genome accession: NZ_CP142354
• Coordinates: 54543..55541 (+)
• Length: 332 a.a.
• NCBI ID: WP_002986679.1
• Uniprot ID: A2RC05
• Organism: Streptococcus pyogenes strain 6745-99
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 49543..60541

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP53_RS00320 (VKP53_00320)	-	50121..50669 (+)	549	WP_228631688.1	hypothetical protein	-
VKP53_RS00325 (VKP53_00325)	-	50680..51048 (+)	369	WP_228631690.1	hypothetical protein	-
VKP53_RS00330 (VKP53_00330)	-	51051..51620 (+)	570	WP_032460531.1	hypothetical protein	-
VKP53_RS00335 (VKP53_00335)	-	51807..51986 (+)	180	WP_032460530.1	hypothetical protein	-
VKP53_RS00340 (VKP53_00340)	purB	51983..53275 (+)	1293	WP_326674817.1	adenylosuccinate lyase	-
VKP53_RS00345 (VKP53_00345)	comR	53406..54317 (+)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
VKP53_RS09030	comS	54401..54496 (+)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
VKP53_RS00350 (VKP53_00350)	ruvB	54543..55541 (+)	999	WP_002986679.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
VKP53_RS00355 (VKP53_00355)	-	55679..56116 (+)	438	WP_002994668.1	low molecular weight protein-tyrosine-phosphatase	-
VKP53_RS00360 (VKP53_00360)	-	56139..56540 (+)	402	WP_032460528.1	MORN repeat-containing protein	-
VKP53_RS00365 (VKP53_00365)	-	56537..58312 (+)	1776	WP_032460527.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37565.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=840465 VKP53_RS00350 WP_002986679.1 54543..55541(+) (ruvB) [Streptococcus pyogenes strain 6745-99]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=840465 VKP53_RS00350 WP_002986679.1 54543..55541(+) (ruvB) [Streptococcus pyogenes strain 6745-99]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCCTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGGCCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: A2RC05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473