Detailed information NTG0840227

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: VKP55_RS05355
• Genome accession: NZ_CP142351
• Coordinates: 1076465..1078708 (-)
• Length: 747 a.a.
• NCBI ID: WP_326673877.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SS1366
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1071465..1083708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP55_RS05330 (VKP55_05330)	-	1072110..1073330 (+)	1221	WP_111674951.1	DUF3114 domain-containing protein	-
VKP55_RS05335 (VKP55_05335)	-	1073444..1074111 (-)	668	Protein_1010	serine hydrolase	-
VKP55_RS05340 (VKP55_05340)	-	1074258..1074485 (-)	228	WP_032462850.1	hypothetical protein	-
VKP55_RS05345 (VKP55_05345)	sodA	1074652..1075257 (-)	606	WP_032462849.1	superoxide dismutase SodA	-
VKP55_RS05350 (VKP55_05350)	holA	1075354..1076394 (-)	1041	WP_136117765.1	DNA polymerase III subunit delta	-
VKP55_RS05355 (VKP55_05355)	comEC/celB	1076465..1078708 (-)	2244	WP_326673877.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
VKP55_RS05360 (VKP55_05360)	comEA/celA/cilE	1078689..1079351 (-)	663	WP_002995626.1	ComEA family DNA-binding protein	Machinery gene
VKP55_RS05365 (VKP55_05365)	-	1079551..1080291 (-)	741	WP_326673879.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
VKP55_RS05370 (VKP55_05370)	-	1080409..1081185 (+)	777	WP_002994360.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
VKP55_RS05375 (VKP55_05375)	-	1081175..1081453 (+)	279	WP_002989164.1	GIY-YIG nuclease family protein	-
VKP55_RS05380 (VKP55_05380)	-	1081477..1083477 (-)	2001	WP_002994363.1	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85660.57 Da
• Isoelectric Point: 9.6101

>NTDB_id=840227 VKP55_RS05355 WP_326673877.1 1076465..1078708(-) (comEC/celB) [Streptococcus pyogenes strain SS1366]
MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICLLVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLE
IQPVQITSVALVPDSIRINGDQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRRMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRVLLLLAVPLEWLKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDVHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPISMVLTALLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVITCGLVIALTLLS
VKYPLTNEVTFIDICQEDSILVREWTGKNLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQALYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=840227 VKP55_RS05355 WP_326673877.1 1076465..1078708(-) (comEC/celB) [Streptococcus pyogenes strain SS1366]
ATGACATTTTCTTGGACTAAGCTAGTGCCCCTGTCAAAGATTCAATTTGCTTTTTTAATCTTGGTTCTCTTTTATCAAAT
CCATAGCCCTAGCTGGTTAACGTTTCTCCTTAGCCTTAGTTTGATTTGCTTACTTGTCAAGCGTTTGTCTAAAAAAGAAT
TTCTCGGTGTCTTTGCCATCCTTAGTTTCTGTGCTTTGTTTTTGCTGTATCAGAAACAGCAGTTGGTTCAAAAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGCATTAGTTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTCTTGG
ACGTCATGGGAAACATTCTTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAGAAAGAGCACC
GTTGGTTAGTGATGCACGCAAAAGTGACATTGGAAAAAGCTGAGGAAGTTCGAAATTTTAAAGGCTTTAATTATCAGACT
TTTTTGGCTTATCAAGGAATTTACAGGATAGGGAAGGTAGAGCAAATAGAACAGCTTGAAGTGATTTCACCCGAGTCAAT
ATGTGACTATTTGTCCTCTTTAAGACGGCGAGCCATTGTTCATTGCCAGCAGCATTTTCCAAGACGTATGTCTCACTACC
TGACGGGCCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGTCAGTTGGGTATCATTCAT
CTCTTTGCTTTATCAGGGATGCAGGTTGGCTTCTTTCTCACTTGTTTTAGAAGGGTGTTGCTATTACTCGCAGTTCCTTT
GGAATGGCTAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGTTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGAATAAAAGGATTAGACAATCTCGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGTCCATTTCTTAATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGTCTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCAATATCAATGGTCTTAACAGCTCTCTTGTCTTATCTCTTTGACCTTTTTATTTTGCCCCTTCTT
TGTCTGGTTTTTTGTCTATCCCCTTTGGTGACTGTCTCAATATGCAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTCGGAAATACTTTCAATAGTTCCCTTGTTTTTGGAAGCCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTTTTTATGATTATCGGCAGGTGCGACAACGAGTTATCACTTGCGGTTTGGTTATAGCGTTGACGCTTTTGTCT
GTCAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTTGCCAGGAAGATAGTATTTTGGTGAGGGAGTGGACAGG
GAAAAATCTCTTAATAGATGTAGGTGGGCGCCCTTTCTTTTCTTCAAAAGAGCACTGGCGACGAGGACATCACGTAGCTA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGTATTCACACAATTGACCAACTATTAGTAACTCACGCAGAT
ACTGATCATATGGGGGATATCGAAGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGTCAAGGCAGTTTAAG
CCATCCAAGCTTTGTTAGGCGGCTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAGTTGCCTATTA
TGGGAAGTGTCTTACAGGCACTCTATCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGACTTGGAAAAAGAGGGGGAAAACGAGATCATAAAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCTTAGCCCGTTTGGAAGACAGA
CAAATTACTTATTACCGAACGGATACGCAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

• Competence protein (Competence) (217-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	45.917	100	0.459
comEC/celB	Streptococcus mitis NCTC 12261	45.71	99.866	0.456
comEC/celB	Streptococcus pneumoniae TIGR4	44.712	100	0.447
comEC/celB	Streptococcus pneumoniae Rx1	44.519	100	0.446
comEC/celB	Streptococcus pneumoniae D39	44.519	100	0.446
comEC/celB	Streptococcus pneumoniae R6	44.519	100	0.446
comEC	Lactococcus lactis subsp. cremoris KW2	40	99.732	0.399