Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF   Type   Machinery gene
Locus tag   QPL68_RS01995 Genome accession   NZ_CP126629
Coordinates   379811..380308 (+) Length   165 a.a.
NCBI ID   WP_001825340.1    Uniprot ID   A0A2S6DDC2
Organism   Staphylococcus aureus strain 35-42     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 374811..385308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QPL68_RS01955 (QPL68_01955) - 374855..375841 (+) 987 WP_000161315.1 ROK family glucokinase -
  QPL68_RS01960 (QPL68_01960) - 375841..376170 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  QPL68_RS01965 (QPL68_01965) - 376167..376790 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  QPL68_RS01970 (QPL68_01970) comGA 376842..377816 (+) 975 WP_259378637.1 competence type IV pilus ATPase ComGA Machinery gene
  QPL68_RS01975 (QPL68_01975) comGB 377788..378858 (+) 1071 WP_109162035.1 competence type IV pilus assembly protein ComGB Machinery gene
  QPL68_RS01980 (QPL68_01980) comGC 378872..379183 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  QPL68_RS01985 (QPL68_01985) comGD 379161..379607 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  QPL68_RS01990 (QPL68_01990) comGE 379594..379893 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  QPL68_RS01995 (QPL68_01995) comGF 379811..380308 (+) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  QPL68_RS02000 (QPL68_02000) - 380405..380551 (+) 147 WP_001789879.1 hypothetical protein -
  QPL68_RS02005 (QPL68_02005) - 380541..381065 (+) 525 WP_029549655.1 shikimate kinase -
  QPL68_RS02010 (QPL68_02010) gcvT 381224..382315 (+) 1092 WP_063652124.1 glycine cleavage system aminomethyltransferase GcvT -
  QPL68_RS02015 (QPL68_02015) gcvPA 382335..383681 (+) 1347 WP_000019698.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  QPL68_RS02020 (QPL68_02020) gcvPB 383674..385146 (+) 1473 WP_063652129.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPB -

Sequence

Protein


Download         Length: 165 a.a.        Molecular weight: 19179.92 Da        Isoelectric Point: 10.2192

>NTDB_id=839281 QPL68_RS01995 WP_001825340.1 379811..380308(+) (comGF) [Staphylococcus aureus strain 35-42]
MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDI
LEDFKGVDRNDIEIRQQRIILHKGEEMIEYKLINNKIIKVVNDRGNITLINNVTAFTANIYYKSIIKITITVKVGTNLQT
KTIYV

Nucleotide


Download         Length: 498 bp        

>NTDB_id=839281 QPL68_RS01995 WP_001825340.1 379811..380308(+) (comGF) [Staphylococcus aureus strain 35-42]
ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT
TAATGTCAAAGCTTTTTCGCTTATTGAAATGTTAGTAGCGATGATGGTTATAAGTATAACTTTACTAATTGTTCCAGACT
TAATTAGACTTAGCAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT
CTAGAGGATTTTAAAGGAGTAGATAGAAACGATATTGAAATTAGGCAACAGCGTATCATTTTACATAAAGGTGAAGAAAT
GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACATTGATTAATAATGTTA
CAGCATTTACTGCAAATATCTACTATAAATCTATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATCTGCAGACT
AAAACTATTTATGTATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(28-51)

Putative Competence protein ComGF (ComGF)

(68-155)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DDC2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF Staphylococcus aureus N315

98.182

100

0.982
  comGF Staphylococcus aureus MW2

96.97

100

0.97