Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QMM73_RS09255 Genome accession   NZ_AP027135
Coordinates   1906602..1907225 (-) Length   207 a.a.
NCBI ID   WP_061838963.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JP089     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1901602..1912225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM73_RS09230 (JP089_17430) - 1901982..1903178 (-) 1197 WP_000238227.1 exonuclease SbcCD subunit D -
  QMM73_RS09235 - 1903475..1903573 (-) 99 WP_061838964.1 hypothetical protein -
  QMM73_RS09240 (JP089_17440) - 1904066..1904410 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  QMM73_RS09245 (JP089_17450) - 1904479..1905603 (-) 1125 WP_000992524.1 DUF445 domain-containing protein -
  QMM73_RS09250 (JP089_17460) - 1905782..1906246 (-) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  QMM73_RS09255 (JP089_17470) vraR 1906602..1907225 (-) 624 WP_061838963.1 response regulator transcription factor Regulator
  QMM73_RS09260 (JP089_17480) - 1907247..1908359 (-) 1113 WP_000437970.1 GAF domain-containing sensor histidine kinase -
  QMM73_RS09265 (JP089_17490) - 1908522..1909343 (+) 822 WP_000669376.1 RluA family pseudouridine synthase -
  QMM73_RS09270 (JP089_17500) fumC 1909806..1911191 (-) 1386 WP_000116229.1 class II fumarate hydratase -
  QMM73_RS09275 (JP089_17510) - 1911387..1911782 (-) 396 WP_061838962.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23894.62 Da        Isoelectric Point: 6.0342

>NTDB_id=83903 QMM73_RS09255 WP_061838963.1 1906602..1907225(-) (vraR) [Staphylococcus aureus strain JP089]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKKHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=83903 QMM73_RS09255 WP_061838963.1 1906602..1907225(-) (vraR) [Staphylococcus aureus strain JP089]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAAAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

34.685

100

0.372
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362

Multiple sequence alignment