Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R8570_RS08565 Genome accession   NZ_AP026932
Coordinates   1705981..1706640 (+) Length   219 a.a.
NCBI ID   WP_000565010.1    Uniprot ID   Q8DNN1
Organism   Streptococcus pneumoniae strain PZ900701549     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1700981..1711640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8570_RS08540 (PC1528_17170) - 1701286..1701603 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  R8570_RS08545 (PC1528_17180) - 1701618..1702514 (-) 897 WP_000825669.1 PEP phosphonomutase -
  R8570_RS08550 (PC1528_17190) - 1702517..1703779 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  R8570_RS08555 (PC1528_17200) - 1704059..1705237 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  R8570_RS08560 (PC1528_17210) - 1705513..1705911 (-) 399 WP_000155403.1 N-acetyltransferase -
  R8570_RS08565 (PC1528_17220) cclA/cilC 1705981..1706640 (+) 660 WP_000565010.1 A24 family peptidase Machinery gene
  R8570_RS08570 (PC1528_17230) - 1706692..1707843 (-) 1152 WP_000481756.1 XRE family transcriptional regulator -
  R8570_RS08575 (PC1528_17240) - 1707858..1708589 (-) 732 WP_000934016.1 hypothetical protein -
  R8570_RS08580 - 1708809..1708919 (+) 111 Protein_1697 prepilin peptidase -
  R8570_RS08585 (PC1528_17250) trpA 1708891..1709667 (-) 777 WP_050102522.1 tryptophan synthase subunit alpha -
  R8570_RS08590 (PC1528_17260) trpB 1709660..1710883 (-) 1224 WP_000331293.1 tryptophan synthase subunit beta -
  R8570_RS08595 (PC1528_17270) - 1710861..1711460 (-) 600 WP_050099763.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24845.99 Da        Isoelectric Point: 7.5762

>NTDB_id=83543 R8570_RS08565 WP_000565010.1 1705981..1706640(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900701549]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=83543 R8570_RS08565 WP_000565010.1 1705981..1706640(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900701549]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DNN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

100

100

1
  cclA/cilC Streptococcus pneumoniae D39

100

100

1
  cclA/cilC Streptococcus pneumoniae R6

100

100

1
  cclA/cilC Streptococcus pneumoniae TIGR4

94.977

100

0.95
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment