Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   U2W45_RS05745 Genome accession   NZ_CP140117
Coordinates   1138055..1139017 (-) Length   320 a.a.
NCBI ID   WP_010922426.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NV1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1133055..1144017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2W45_RS05730 (U2W45_05725) - 1133892..1134599 (-) 708 WP_002989211.1 O-methyltransferase -
  U2W45_RS05735 (U2W45_05730) - 1134665..1135861 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  U2W45_RS05740 (U2W45_05735) pepF 1136237..1138042 (-) 1806 WP_010922425.1 oligoendopeptidase F Regulator
  U2W45_RS05745 (U2W45_05740) coiA 1138055..1139017 (-) 963 WP_010922426.1 competence protein CoiA Machinery gene
  U2W45_RS05750 (U2W45_05745) - 1139312..1140028 (-) 717 WP_002995774.1 pseudouridine synthase -
  U2W45_RS05755 (U2W45_05750) nagB 1140147..1140851 (-) 705 WP_010922428.1 glucosamine-6-phosphate deaminase -
  U2W45_RS05760 (U2W45_05755) queA 1141053..1142081 (+) 1029 WP_010922429.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  U2W45_RS05765 (U2W45_05760) - 1142088..1143308 (+) 1221 WP_010922430.1 DUF3114 domain-containing protein -
  U2W45_RS05770 (U2W45_05765) - 1143422..1144012 (-) 591 WP_010922431.1 serine hydrolase -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37859.28 Da        Isoelectric Point: 10.2431

>NTDB_id=833628 U2W45_RS05745 WP_010922426.1 1138055..1139017(-) (coiA) [Streptococcus pyogenes strain NV1]
MTKILTALDDKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=833628 U2W45_RS05745 WP_010922426.1 1138055..1139017(-) (coiA) [Streptococcus pyogenes strain NV1]
GTGACAAAAATATTAACCGCTTTAGATGATAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGGTTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.329

100

0.403