Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   U0533_RS09460 Genome accession   NZ_CP139953
Coordinates   1932390..1933049 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain Nord1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1927390..1938049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0533_RS09430 (U0533_09430) - 1927506..1928453 (+) 948 WP_001305988.1 iron-siderophore ABC transporter substrate-binding protein -
  U0533_RS09435 (U0533_09435) - 1928450..1929337 (+) 888 WP_000614953.1 MurR/RpiR family transcriptional regulator -
  U0533_RS09440 (U0533_09440) ygiN 1929382..1929696 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  U0533_RS09445 (U0533_09445) mdaB 1929727..1930308 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  U0533_RS09450 (U0533_09450) ygiZ 1930666..1930995 (+) 330 WP_001551659.1 DUF2645 family protein -
  U0533_RS09455 (U0533_09455) qseC 1931044..1932393 (-) 1350 WP_001551658.1 quorum sensing histidine kinase QseC -
  U0533_RS09460 (U0533_09460) ciaR 1932390..1933049 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  U0533_RS09465 (U0533_09465) ygiW 1933201..1933593 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  U0533_RS09470 (U0533_09470) ygiV 1933646..1934128 (+) 483 WP_000183492.1 AraC family transcriptional regulator -
  U0533_RS09475 (U0533_09475) ygiS 1934237..1935844 (+) 1608 WP_001551657.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=832862 U0533_RS09460 WP_001221493.1 1932390..1933049(-) (ciaR) [Escherichia coli strain Nord1]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=832862 U0533_RS09460 WP_001221493.1 1932390..1933049(-) (ciaR) [Escherichia coli strain Nord1]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGTGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGTTAGCGGAACGTGTAGAGGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAACTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACTCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365