Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   U0448_RS05475 Genome accession   NZ_CP139860
Coordinates   1072557..1072793 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 1067557..1077793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS05465 - 1071250..1071459 (+) 210 Protein_1027 transposase -
  U0448_RS05470 - 1071494..1072291 (-) 798 Protein_1028 transposase -
  U0448_RS05475 comW 1072557..1072793 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  U0448_RS05480 - 1073024..1074310 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  U0448_RS05485 tadA 1074511..1074978 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  U0448_RS05495 - 1075165..1075608 (+) 444 WP_000701992.1 dUTP diphosphatase -
  U0448_RS05500 - 1075610..1076125 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  U0448_RS05505 radA 1076139..1077500 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=832099 U0448_RS05475 WP_000939546.1 1072557..1072793(+) (comW) [Streptococcus pneumoniae strain 21011]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=832099 U0448_RS05475 WP_000939546.1 1072557..1072793(+) (comW) [Streptococcus pneumoniae strain 21011]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756