NTDB

Overview

Name	cclA/cilC	Type	Machinery gene
Locus tag	QL280_RS08110	Genome accession	NZ_CP125291
Coordinates	1606986..1607645 (+)	Length	219 a.a.
NCBI ID	WP_000565001.1	Uniprot ID	A0A0B7M7B9
Organism	Streptococcus pneumoniae strain 105_Kz
Function	processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1601986..1612645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QL280_RS08085 (QL280_08085)	-	1602291..1602608 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
QL280_RS08090 (QL280_08090)	-	1602623..1603519 (-)	897	WP_000825667.1	PEP phosphonomutase	-
QL280_RS08095 (QL280_08095)	-	1603522..1604784 (-)	1263	WP_000413342.1	PTS sugar transporter subunit IIC	-
QL280_RS08100 (QL280_08100)	-	1605064..1606242 (+)	1179	WP_000175876.1	ROK family transcriptional regulator	-
QL280_RS08105 (QL280_08105)	-	1606470..1606916 (-)	447	WP_000155399.1	GNAT family N-acetyltransferase	-
QL280_RS08110 (QL280_08110)	cclA/cilC	1606986..1607645 (+)	660	WP_000565001.1	A24 family peptidase	Machinery gene
QL280_RS08115 (QL280_08115)	-	1607697..1608848 (-)	1152	WP_000481756.1	XRE family transcriptional regulator	-
QL280_RS08120 (QL280_08120)	-	1608863..1609594 (-)	732	WP_000934017.1	hypothetical protein	-
QL280_RS08125 (QL280_08125)	-	1609823..1609924 (+)	102	Protein_1612	prepilin peptidase	-
QL280_RS08130 (QL280_08130)	trpA	1609896..1610672 (-)	777	WP_001127015.1	tryptophan synthase subunit alpha	-
QL280_RS08135 (QL280_08135)	trpB	1610665..1611888 (-)	1224	WP_000331292.1	tryptophan synthase subunit beta	-
QL280_RS08140 (QL280_08140)	-	1611866..1612465 (-)	600	WP_000169898.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

Download Length: 219 a.a. Molecular weight: 24820.92 Da Isoelectric Point: 7.2761

                                >NTDB_id=830831 QL280_RS08110 WP_000565001.1 1606986..1607645(+) (cclA/cilC) [Streptococcus pneumoniae strain 105_Kz]

MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG

LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL

FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

Download Length: 660 bp

                                >NTDB_id=830831 QL280_RS08110 WP_000565001.1 1606986..1607645(+) (cclA/cilC) [Streptococcus pneumoniae strain 105_Kz]

ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA

ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC

AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA

CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT

ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA

ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC

TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT

GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG

GTAAGCTACTACTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0B7M7B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
cclA/cilC	Streptococcus pneumoniae TIGR4	98.174	100	0.982
cclA/cilC	Streptococcus pneumoniae Rx1	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae D39	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae R6	96.804	100	0.968
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	87.215	100	0.872

Detailed information NTG0830831