Detailed information NTG0830815

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: QL280_RS04390
• Genome accession: NZ_CP125291
• Coordinates: 867231..868184 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 105_Kz
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 862231..873184

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QL280_RS04365 (QL280_04365)	rpmG	862974..863123 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
QL280_RS04370 (QL280_04370)	secG	863163..863396 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
QL280_RS04375 (QL280_04375)	rnr	863498..865852 (+)	2355	WP_000654923.1	ribonuclease R	-
QL280_RS04380 (QL280_04380)	smpB	865815..866282 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
QL280_RS04385 (QL280_04385)	tehB	866298..867158 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
QL280_RS04390 (QL280_04390)	coiA	867231..868184 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
QL280_RS04395 (QL280_04395)	pepF	868203..870005 (+)	1803	WP_000244144.1	oligoendopeptidase F	Regulator
QL280_RS04400 (QL280_04400)	-	870007..870720 (+)	714	WP_000230401.1	O-methyltransferase	-
QL280_RS04405 (QL280_04405)	prsA	870787..871728 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
QL280_RS04410 (QL280_04410)	-	871847..872188 (-)	342	Protein_871	IS3 family transposase	-
QL280_RS04415 (QL280_04415)	-	872602..872697 (+)	96	Protein_872	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=830815 QL280_RS04390 WP_000495909.1 867231..868184(+) (coiA) [Streptococcus pneumoniae strain 105_Kz]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=830815 QL280_RS04390 WP_000495909.1 867231..868184(+) (coiA) [Streptococcus pneumoniae strain 105_Kz]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435