Detailed information NTG0083008

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: R8623_RS01320
• Genome accession: NZ_AP026928
• Coordinates: 231710..232708 (+)
• Length: 332 a.a.
• NCBI ID: WP_001860761.1
• Uniprot ID: C1CC50
• Organism: Streptococcus pneumoniae strain PZ900700406
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 226710..237708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8623_RS01300 (PC0401_02490)	leuS	226851..229352 (+)	2502	WP_130897368.1	leucine--tRNA ligase	-
R8623_RS01305 (PC0401_02500)	-	229546..230241 (+)	696	WP_044813435.1	GNAT family N-acetyltransferase	-
R8623_RS01310 (PC0401_02510)	-	230253..230669 (+)	417	WP_044813436.1	GNAT family N-acetyltransferase	-
R8623_RS01315	-	231484..231576 (-)	93	WP_000970381.1	type I toxin-antitoxin system Fst family toxin	-
R8623_RS01320 (PC0401_02520)	ruvB	231710..232708 (+)	999	WP_001860761.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
R8623_RS01325 (PC0401_02530)	-	232689..233261 (+)	573	WP_001098895.1	nucleotidyltransferase family protein	-
R8623_RS01330 (PC0401_02540)	-	233492..234250 (+)	759	WP_000466714.1	isoprenyl transferase	-
R8623_RS01335 (PC0401_02550)	-	234259..235062 (+)	804	WP_000189848.1	phosphatidate cytidylyltransferase	-
R8623_RS01340 (PC0401_02560)	eeP	235084..236343 (+)	1260	WP_000900660.1	RIP metalloprotease RseP	Regulator

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37230.69 Da
• Isoelectric Point: 4.5393

>NTDB_id=83008 R8623_RS01320 WP_001860761.1 231710..232708(+) (ruvB) [Streptococcus pneumoniae strain PZ900700406]
MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPVIEKAGDLVAILNELEPGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRVRDFAQIMGNGVID
DIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAK
AYEHLGYEYSEK

Nucleotide

• Length: 999 bp

>NTDB_id=83008 R8623_RS01320 WP_001860761.1 231710..232708(+) (ruvB) [Streptococcus pneumoniae strain PZ900700406]
ATGAGTAGAATTTTAGATAATGAGATAATGGGGGATGAGGAGTTAGTAGAACGCACGCTCCGTCCTCAGTATTTACGTGA
ATATATCGGACAGGATAAGGTCAAGGACCAGCTACAAATCTTTATTGAAGCTGCCAAAATGCGGGATGAAGCGCTGGATC
ATGTGCTCTTATTTGGGCCTCCAGGTCTCGGGAAAACGACCATGGCCTTTGTTATTGCCAACGAACTGGGAGTCAATCTT
AAGCAGACGTCGGGTCCAGTCATTGAAAAAGCCGGAGATCTGGTAGCTATTTTGAATGAGTTAGAGCCTGGGGATGTACT
TTTTATTGATGAGATCCATCGTTTGCCAATGTCAGTGGAAGAGGTGCTTTATAGTGCTATGGAGGACTTCTACATCGATA
TTATGATTGGGGCTGGTGAGGGTAGTCGTAGTGTTCATTTGGAGTTACCACCTTTTACCTTGATTGGTGCGACGACTCGG
GCTGGTATGCTCTCCAATCCGCTACGGGCACGTTTTGGGATTACAGGCCATATGGAGTATTATGCCCATGCTGGCTTGAC
AGAAATTGTCGAGCGGACGGCAGATATTTTTGAGATGGAAATCACTCATGAGGCAGCATCTGAGTTGGCCCTACGTAGTC
GTGGGACCCCTCGTATTGCCAATCGTCTCCTCAAGCGCGTGCGCGATTTTGCCCAGATAATGGGGAATGGGGTAATTGAT
GATATTATTACCGATAAGGCTTTGACTATGCTGGATGTTGACCATGAAGGTTTGGACTATGTGGATCAAAAAATCCTTCG
TACCATGATTGAGATGTACAGTGGAGGACCTGTTGGTCTAGGAACTCTTTCTGTGAATATCGCCGAAGAGCGTGAGACAG
TTGAAGATATGTATGAGCCTTACTTGATTCAAAAAGGTTTTATCATGCGGACACGGTCTGGACGGGTGGCGACTGCTAAG
GCATATGAGCACTTAGGTTATGAATACAGTGAAAAATAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: C1CC50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	99.699	100	0.997
ruvB	Streptococcus pneumoniae D39	99.699	100	0.997
ruvB	Streptococcus pneumoniae TIGR4	98.795	100	0.988
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.429	98.193	0.593
ruvB	Helicobacter pylori 26695	50.774	97.289	0.494
ruvB	Synechocystis sp. PCC 6803	48.193	100	0.482