NTDB

Overview

Name	vicR	Type	Regulator
Locus tag	QLH56_RS08920	Genome accession	NZ_CP125107
Coordinates	1834586..1835311 (+)	Length	241 a.a.
NCBI ID	WP_003101290.1	Uniprot ID	A0A3L8GIX6
Organism	Streptococcus iniae strain DFSM220524
Function	repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1829586..1840311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QLH56_RS08890 (QLH56_08890)	-	1829693..1831069 (+)	1377	WP_003101303.1	PTS sugar transporter subunit IIC	-
QLH56_RS08895 (QLH56_08895)	-	1831356..1831982 (+)	627	WP_003101299.1	NAD(P)H-binding protein	-
QLH56_RS08900 (QLH56_08900)	-	1832054..1832869 (-)	816	WP_016356078.1	TIGR03943 family protein	-
QLH56_RS08905 (QLH56_08905)	-	1832866..1833771 (-)	906	WP_003101296.1	permease	-
QLH56_RS08910 (QLH56_08910)	-	1833771..1833914 (-)	144	WP_003101294.1	SPJ_0845 family protein	-
QLH56_RS08915 (QLH56_08915)	-	1834107..1834490 (+)	384	WP_003101292.1	VOC family protein	-
QLH56_RS08920 (QLH56_08920)	vicR	1834586..1835311 (+)	726	WP_003101290.1	response regulator transcription factor	Regulator
QLH56_RS08925 (QLH56_08925)	-	1835295..1836623 (+)	1329	WP_003101288.1	ATP-binding protein	-
QLH56_RS08930 (QLH56_08930)	-	1836777..1837457 (+)	681	WP_016356077.1	substrate-binding domain-containing protein	-
QLH56_RS08935 (QLH56_08935)	pstC	1837520..1838383 (+)	864	WP_003101285.1	phosphate ABC transporter permease subunit PstC	-
QLH56_RS08940 (QLH56_08940)	pstA	1838376..1839191 (+)	816	WP_003101283.1	phosphate ABC transporter permease PstA	-
QLH56_RS08945 (QLH56_08945)	-	1839194..1839805 (+)	612	WP_016356076.1	phosphate ABC transporter ATP-binding protein	-

Sequence

Protein

Download Length: 241 a.a. Molecular weight: 28088.34 Da Isoelectric Point: 5.1365

                                >NTDB_id=829986 QLH56_RS08920 WP_003101290.1 1834586..1835311(+) (vicR) [Streptococcus iniae strain DFSM220524]

MKKTVLLVDDEEHILRLLDYHLSKEGFSIDTATDGRSALKLAETESYDFILLDIMLPQLDGIEVCKRIRAKNSKTPIMMV

SAKGEEFDKVLALELGADDYMTKPFSPRELLARVKAILRRTGKDDSQQEEFGFADQRFLVNDLVIYPERNEVYKEQDLIS

LTPKEYELLMYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDDPKNPEMIKTIRGYGYQFKEMKDATK

S

Nucleotide

Download Length: 726 bp

                                >NTDB_id=829986 QLH56_RS08920 WP_003101290.1 1834586..1835311(+) (vicR) [Streptococcus iniae strain DFSM220524]

ATGAAAAAGACAGTTTTATTAGTAGACGACGAAGAGCACATCTTACGTTTATTAGACTATCATCTCAGCAAGGAAGGCTT

TAGTATTGACACAGCAACAGATGGCAGATCAGCACTAAAATTAGCTGAAACAGAAAGTTATGACTTCATTTTGTTAGACA

TCATGTTGCCCCAATTGGACGGTATTGAGGTCTGTAAACGTATCAGAGCTAAAAATAGTAAGACCCCTATTATGATGGTA

TCAGCTAAAGGGGAAGAATTTGACAAGGTCCTAGCCTTAGAACTAGGAGCTGATGATTACATGACAAAACCCTTTAGTCC

AAGGGAATTGCTGGCGCGTGTAAAAGCTATTTTAAGACGAACAGGAAAAGACGACAGCCAACAAGAAGAGTTTGGCTTCG

CTGACCAGCGATTCTTGGTCAATGACTTGGTCATTTACCCTGAAAGAAATGAAGTTTACAAAGAGCAAGACTTGATTTCC

TTAACCCCAAAAGAGTATGAACTGTTAATGTATTTAGTCAAACATCCCAATATGACCTTAACAAGAGAACGACTTTTAGA

ACGGATTTGGGGGTATGACTTTGGCCAAGAAACACGTTTAGTAGATGTTCATATTGGAAAATTAAGAGACAAAATTGAAG

ATGATCCTAAAAATCCAGAGATGATTAAAACAATCAGGGGCTATGGCTATCAGTTTAAGGAGATGAAGGATGCTACAAAA

TCTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A3L8GIX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
vicR	Streptococcus mutans UA159	51.293	96.266	0.494
micA	Streptococcus pneumoniae Cp1015	48.918	95.851	0.469
covR	Lactococcus lactis subsp. lactis strain DGCC12653	42.194	98.34	0.415
covR	Streptococcus salivarius strain HSISS4	39.316	97.095	0.382

Detailed information NTG0829986