Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   R8623_RS00115 Genome accession   NZ_AP026928
Coordinates   22169..22405 (+) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 17169..27405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS00105 - 20225..21071 (+) 847 Protein_14 IS630 family transposase -
  R8623_RS00110 - 21106..21903 (-) 798 Protein_15 transposase -
  R8623_RS00115 (PC0401_00180) comW 22169..22405 (+) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  R8623_RS00120 (PC0401_00190) - 22636..23922 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  R8623_RS00125 (PC0401_00200) tadA 24123..24590 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  R8623_RS00135 (PC0401_00210) - 24799..25497 (-) 699 WP_001106362.1 site-specific integrase -
  R8623_RS00140 (PC0401_00220) - 25587..25940 (-) 354 WP_001814135.1 hypothetical protein -
  R8623_RS00145 (PC0401_00230) - 25995..27059 (-) 1065 WP_061374999.1 type I restriction endonuclease -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=82998 R8623_RS00115 WP_000939544.1 22169..22405(+) (comW) [Streptococcus pneumoniae strain PZ900700406]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=82998 R8623_RS00115 WP_000939544.1 22169..22405(+) (comW) [Streptococcus pneumoniae strain PZ900700406]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

78.205

100

0.782
  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769

Multiple sequence alignment