Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   H7679_RS08540 Genome accession   NZ_AP023392
Coordinates   1740260..1740904 (+) Length   214 a.a.
NCBI ID   WP_024396126.1    Uniprot ID   A0A0Z8EJ61
Organism   Streptococcus suis strain DAT300     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1735260..1745904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS08515 (DAT300_16530) - 1735919..1737256 (-) 1338 WP_002942867.1 hemolysin family protein -
  H7679_RS08520 (DAT300_16540) - 1737389..1738168 (+) 780 WP_024396130.1 ABC transporter ATP-binding protein -
  H7679_RS08525 (DAT300_16550) - 1738184..1738738 (-) 555 WP_024396129.1 tRNA (mnm(5)s(2)U34)-methyltransferase -
  H7679_RS08530 (DAT300_16560) - 1738748..1739266 (-) 519 WP_024396128.1 TetR/AcrR family transcriptional regulator -
  H7679_RS08535 (DAT300_16570) - 1739388..1740206 (+) 819 WP_024396127.1 cation diffusion facilitator family transporter -
  H7679_RS08540 cclA/cilC 1740260..1740904 (+) 645 WP_024396126.1 prepilin peptidase Machinery gene
  H7679_RS08545 (DAT300_16580) - 1741012..1742472 (+) 1461 WP_024396125.1 nicotinate phosphoribosyltransferase -
  H7679_RS08550 (DAT300_16590) nadE 1742485..1743309 (+) 825 WP_024396124.1 ammonia-dependent NAD(+) synthetase -
  H7679_RS08555 (DAT300_16600) trpB 1743352..1744527 (-) 1176 WP_015647230.1 tryptophan synthase subunit beta -
  H7679_RS08560 (DAT300_16610) - 1745347..1745874 (-) 528 WP_024396123.1 VanZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24255.27 Da        Isoelectric Point: 8.4760

>NTDB_id=82960 H7679_RS08540 WP_024396126.1 1740260..1740904(+) (cclA/cilC) [Streptococcus suis strain DAT300]
MKTIILFFLGASIGSFLGLVIDRFPEQSIISPSSHCNACKRRLKAWDLIPILSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILSLAGLVLTIYDIKHQEYPFAVWLVFTFTALVLSQLNWLFCGFLLLAYLTEKWQFNIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFTIFKPKSIPYVPLLFLSSIPIILCI

Nucleotide


Download         Length: 645 bp        

>NTDB_id=82960 H7679_RS08540 WP_024396126.1 1740260..1740904(+) (cclA/cilC) [Streptococcus suis strain DAT300]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCAATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCTCCCCCTCTAGTCACTGCAATGCCTGCAAGCGACGGCTCAAGGCCTGGGACCTAATACCCATCCTGTCCC
AGCTTTCGACAAAATCTAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGATTGGAATTCTTAGCTGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCAGCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAACATCAGGAATATCCTTTTGCTGTCTGGCTCGTTTTTACTTTTACAGCTCTGGTACTCTCCCAGCTCA
ACTGGCTCTTCTGTGGCTTTTTACTCTTGGCCTATCTAACTGAAAAATGGCAATTCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCACTATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTTTTTCTTTCAAGTATTCCTATCATTCTGTGCA
TCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8EJ61

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.057

99.065

0.486
  cclA/cilC Streptococcus pneumoniae Rx1

48.544

96.262

0.467
  cclA/cilC Streptococcus pneumoniae D39

48.544

96.262

0.467
  cclA/cilC Streptococcus pneumoniae R6

48.544

96.262

0.467
  cclA/cilC Streptococcus pneumoniae TIGR4

47.573

96.262

0.458
  cclA/cilC Streptococcus mitis NCTC 12261

44.811

99.065

0.444

Multiple sequence alignment