Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   H7679_RS04385 Genome accession   NZ_AP023392
Coordinates   861726..863105 (+) Length   459 a.a.
NCBI ID   WP_014635993.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT300     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 856726..868105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS04355 (DAT300_08140) pstA 857185..858072 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  H7679_RS04360 (DAT300_08150) pstB 858097..858900 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  H7679_RS04365 (DAT300_08160) pstB 858912..859670 (+) 759 WP_024395285.1 phosphate ABC transporter ATP-binding protein PstB -
  H7679_RS04370 (DAT300_08170) phoU 859699..860355 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  H7679_RS04375 (DAT300_08180) - 860521..860868 (+) 348 WP_014635995.1 hypothetical protein -
  H7679_RS04380 (DAT300_08190) ciaR 861062..861733 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  H7679_RS04385 (DAT300_08200) ciaH 861726..863105 (+) 1380 WP_014635993.1 sensor histidine kinase Regulator
  H7679_RS04390 (DAT300_08210) - 863205..864434 (+) 1230 WP_024395287.1 transglutaminase domain-containing protein -
  H7679_RS04395 (DAT300_08220) tnpA 864811..865275 (+) 465 WP_002939996.1 IS200/IS605-like element ISSsu4 family transposase -
  H7679_RS04400 (DAT300_08230) rpsT 865417..865665 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  H7679_RS04405 (DAT300_08240) coaA 865724..866644 (-) 921 WP_002940857.1 type I pantothenate kinase -
  H7679_RS04410 (DAT300_08250) - 866753..867343 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51926.60 Da        Isoelectric Point: 6.8975

>NTDB_id=82954 H7679_RS04385 WP_014635993.1 861726..863105(+) (ciaH) [Streptococcus suis strain DAT300]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKEAMVESSFGM
SEDYRYVTIELPTDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDT
DRKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=82954 H7679_RS04385 WP_014635993.1 861726..863105(+) (ciaH) [Streptococcus suis strain DAT300]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAAAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCAACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAATGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGCCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCTTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCAAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACTGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATACC
GATAGGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

48.922

100

0.495
  ciaH Streptococcus pneumoniae D39

48.922

100

0.495
  ciaH Streptococcus pneumoniae R6

48.922

100

0.495
  ciaH Streptococcus pneumoniae TIGR4

48.922

100

0.495
  ciaH Streptococcus mutans UA159

49.888

97.386

0.486

Multiple sequence alignment