Detailed information NTG0082933

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: H7679_RS01060
• Genome accession: NZ_AP023392
• Coordinates: 163059..163493 (+)
• Length: 144 a.a.
• NCBI ID: WP_014637316.1
• Uniprot ID: G7SD64
• Organism: Streptococcus suis strain DAT300
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 158059..168493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7679_RS01020 (DAT300_01700)	-	160075..160341 (+)	267	WP_184495871.1	hypothetical protein	-
H7679_RS01025 (DAT300_01710)	-	160354..160809 (+)	456	WP_184495873.1	hypothetical protein	-
H7679_RS01030 (DAT300_01720)	-	160784..160987 (+)	204	WP_029751977.1	phage holin	-
H7679_RS01035 (DAT300_01730)	-	161117..161827 (+)	711	WP_184495875.1	CHAP domain-containing protein	-
H7679_RS01040 (DAT300_01740)	prx	161973..162158 (+)	186	WP_016056161.1	hypothetical protein	Regulator
H7679_RS01045 (DAT300_01750)	comYC	162159..162419 (+)	261	WP_184495877.1	competence type IV pilus major pilin ComGC	Machinery gene
H7679_RS01050 (DAT300_01760)	comGD	162400..162807 (+)	408	WP_024395446.1	competence type IV pilus minor pilin ComGD	-
H7679_RS01055 (DAT300_01770)	comYE	162779..163072 (+)	294	WP_024394703.1	competence type IV pilus minor pilin ComGE	Machinery gene
H7679_RS01060 (DAT300_01780)	comGF/cglF	163059..163493 (+)	435	WP_014637316.1	competence type IV pilus minor pilin ComGF	Machinery gene
H7679_RS01065 (DAT300_01790)	comGG	163471..163881 (+)	411	WP_044676305.1	competence type IV pilus minor pilin ComGG	-
H7679_RS01070 (DAT300_01800)	comYH	163938..164891 (+)	954	WP_184495879.1	class I SAM-dependent methyltransferase	Machinery gene
H7679_RS01075 (DAT300_01810)	-	164941..166128 (+)	1188	WP_024401510.1	acetate kinase	-
H7679_RS01080 (DAT300_01820)	-	166443..166994 (+)	552	WP_024395442.1	folate family ECF transporter S component	-
H7679_RS01085 (DAT300_01830)	-	167050..168306 (+)	1257	WP_024395441.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16405.75 Da
• Isoelectric Point: 6.9830

>NTDB_id=82933 H7679_RS01060 WP_014637316.1 163059..163493(+) (comGF/cglF) [Streptococcus suis strain DAT300]
MLKSKLPAFTLLECLVALIILSGSLLVFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSRSDDFRKTNDKGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=82933 H7679_RS01060 WP_014637316.1 163059..163493(+) (comGF/cglF) [Streptococcus suis strain DAT300]
TTGTTAAAAAGTAAACTTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCTTTAATCATCCTATCAGGAAGTCTTCTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTACCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGTCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGCGAA
CAGGCTTTGGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAAGGGACAGGGTTACCAGCCCATGCT
CTATCAGGTGGACAGCGCAGCCATTTCCCAAGAAAACCAGCTAGTGCGCATCGACTTTAGCTTTAAAAATGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae D39	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae R6	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae TIGR4	53.191	97.917	0.521
comYF	Streptococcus mutans UA140	50.694	100	0.507
comYF	Streptococcus mutans UA159	50	100	0.5
comGF/cglF	Streptococcus mitis NCTC 12261	53.731	93.056	0.5
comGF/cglF	Streptococcus mitis SK321	51.493	93.056	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	46.809	97.917	0.458