Detailed information NTG0082931

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: R8611_RS05615
• Genome accession: NZ_AP026927
• Coordinates: 1107875..1109863 (-)
• Length: 662 a.a.
• NCBI ID: WP_000607035.1
• Uniprot ID: C1C7L7
• Organism: Streptococcus pneumoniae strain PZ900700178
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1102875..1114863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8611_RS05575 (PC0174_10950)	coaB	1103175..1103864 (+)	690	WP_061694532.1	phosphopantothenate--cysteine ligase	-
R8611_RS05580 (PC0174_10960)	coaC	1103876..1104427 (+)	552	WP_317647819.1	phosphopantothenoylcysteine decarboxylase	-
R8611_RS05585 (PC0174_10970)	-	1104411..1104974 (+)	564	WP_000747408.1	ECF transporter S component	-
R8611_RS05590 (PC0174_10980)	-	1105256..1105783 (+)	528	WP_001097402.1	ECF transporter S component	-
R8611_RS05595 (PC0174_10990)	-	1105795..1106310 (+)	516	WP_000159176.1	transcription repressor NadR	-
R8611_RS05600 (PC0174_11000)	-	1106307..1106774 (-)	468	WP_000091534.1	8-oxo-dGTP diphosphatase	-
R8611_RS05605 (PC0174_11010)	-	1106848..1107336 (-)	489	WP_000216018.1	GNAT family N-acetyltransferase	-
R8611_RS05610 (PC0174_11020)	-	1107302..1107865 (-)	564	WP_000639832.1	GNAT family N-acetyltransferase	-
R8611_RS05615 (PC0174_11030)	uvrB	1107875..1109863 (-)	1989	WP_000607035.1	excinuclease ABC subunit UvrB	Machinery gene
R8611_RS05620 (PC0174_11040)	-	1109940..1110893 (-)	954	WP_000792125.1	CPBP family intramembrane glutamic endopeptidase	-
R8611_RS05625 (PC0174_11050)	-	1111066..1113231 (+)	2166	WP_317647820.1	ABC transporter substrate-binding protein/permease	-
R8611_RS05630 (PC0174_11060)	-	1113231..1113971 (+)	741	WP_001096313.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 662 a.a.
• Molecular weight: 75737.77 Da
• Isoelectric Point: 4.5848

>NTDB_id=82931 R8611_RS05615 WP_000607035.1 1107875..1109863(-) (uvrB) [Streptococcus pneumoniae strain PZ900700178]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide

• Length: 1989 bp

>NTDB_id=82931 R8611_RS05615 WP_000607035.1 1107875..1109863(-) (uvrB) [Streptococcus pneumoniae strain PZ900700178]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTAGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATCCGTGAGGTTGAGGCTCTGACAGGTCAGGTATTG
GGAGAGGTGGATCATTTGGCGATTTTCCCAGCTACTCACTTTGTGACCAATGACGACCATATGGAAGTTGCCGTTGCCAA
GATTCAAGCAGAATTAGAAGAGCAGTTAGCTGTCTTTGAGAAGGAAGGTAAATTGCTTGAAGCCCAGCGCTTGAAACAAC
GGACAGAGTACGATATCGAAATGCTGCGCGAGATGGGCTATACAAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGTAGTGAAGGTGAGCCTCCTTATACGCTTCTCGACTTTTTCCCAGATGATTTTTTGATTATGATTGACGAGAGTCATAT
GACTATGGGACAAATAAAAGGCATGTACAATGGAGACCGTTCGCGTAAGGAAATGCTAGTAAATTATGGTTTCCGTTTAC
CGTCTGCCTTGGACAATCGTCCTCTCCGTCGTGAGGAGTTTGAAAGCCATGTGCATCAGATTGTTTACGTATCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACGGTGATTGAGCAAATCATTCGACCGACAGGGCTTTTGGATCCTGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGATCTCTTAGGTGAAATCAATGCCCGTGTTGAAAAGAATGAACGAACCT
TTATCACCACCTTGACCAAGAAAATGGCAGAGGACTTGACCGACTATTTCAAGGAAATGGGCATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGATCTCCGCTTGGGTGTCTTTGATGTCTTGGTTGGAAT
CAATCTCCTTCGTGAAGGGATTGACGTTCCTGAGGTGAGCCTCGTAGCTATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GTAACGAGCGTGGACTCATCCAGACCATTGGGCGTGCCGCCCGTAACAGTGAAGGTCATGTCATCATGTATGCAGATACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATAGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

• UvrB/uvrC motif (UVR) (626-660)

• Type III restriction enzyme, res subunit (ResIII) (17-143)

• Ultra-violet resistance protein B (UvrB) (556-598)

• Helicase conserved C-terminal domain (Helicase_C) (443-549)

• UvrB interaction domain (UvrB_inter) (164-254)

3D structure

• AlphaFold DB: C1C7L7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	99.849	100	0.998
uvrB	Streptococcus pneumoniae D39	99.849	100	0.998
uvrB	Streptococcus pneumoniae TIGR4	99.698	100	0.997