Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R9806_RS17120 Genome accession   NZ_CP139044
Coordinates   4076976..4077638 (-) Length   220 a.a.
NCBI ID   WP_223779139.1    Uniprot ID   -
Organism   Streptomyces sp. KN37     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4071976..4082638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R9806_RS17100 (R9806_17100) radA/sms 4072620..4074029 (+) 1410 WP_223776021.1 DNA repair protein RadA Machinery gene
  R9806_RS17105 (R9806_17105) disA 4074109..4075233 (+) 1125 WP_223776020.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  R9806_RS17110 (R9806_17110) - 4075278..4076087 (-) 810 WP_223776019.1 hypothetical protein -
  R9806_RS17115 (R9806_17115) - 4076261..4076947 (+) 687 WP_320590287.1 phosphatase PAP2 family protein -
  R9806_RS17120 (R9806_17120) vraR 4076976..4077638 (-) 663 WP_223779139.1 response regulator transcription factor Regulator
  R9806_RS17125 (R9806_17125) - 4077647..4079302 (-) 1656 WP_320590288.1 sensor histidine kinase -
  R9806_RS17130 (R9806_17130) - 4079444..4080379 (+) 936 WP_223776016.1 A/G-specific adenine glycosylase -
  R9806_RS17135 (R9806_17135) - 4080577..4081125 (+) 549 WP_320590289.1 SigE family RNA polymerase sigma factor -
  R9806_RS17140 (R9806_17140) - 4081113..4081757 (+) 645 WP_223776014.1 hypothetical protein -
  R9806_RS17145 (R9806_17145) cseB 4081844..4082557 (+) 714 WP_223776013.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 22780.30 Da        Isoelectric Point: 6.5000

>NTDB_id=829211 R9806_RS17120 WP_223779139.1 4076976..4077638(-) (vraR) [Streptomyces sp. KN37]
MPIRVLLADDEAMIRAGVRAILAAGGDIEVVAEAADGREAVSLAQAHRPDVALLDIRMPRLDGLAAGEEIVRTVPGAAVA
MLTTFSEDAYVARALGGGATGFLLKSGDPHELIAGVRAVAGGAAFLSPKVARHVIDGFGARRMGRGAAARARVQTLTPRE
REVLGLVGAGLSNPEIAARLHLVEGTVKAYVSAVLERLEVKNRVQAAIVAYEAGLVPEAD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=829211 R9806_RS17120 WP_223779139.1 4076976..4077638(-) (vraR) [Streptomyces sp. KN37]
ATGCCCATCCGGGTCCTGCTGGCCGACGACGAGGCCATGATCCGCGCGGGCGTGCGCGCCATCCTGGCCGCGGGCGGGGA
CATCGAGGTCGTCGCCGAGGCCGCCGACGGGCGCGAGGCCGTCTCCCTGGCCCAGGCCCACCGCCCCGACGTGGCGCTGC
TCGACATCCGCATGCCGCGCCTGGACGGGCTCGCCGCGGGCGAGGAGATCGTCCGTACCGTGCCGGGGGCCGCCGTCGCC
ATGCTGACGACGTTCTCCGAAGACGCGTACGTGGCACGGGCGCTGGGCGGCGGCGCCACCGGCTTCCTGCTGAAGTCCGG
CGACCCGCATGAACTCATCGCGGGCGTACGGGCGGTGGCGGGCGGCGCCGCCTTCCTCTCACCGAAGGTGGCCCGGCACG
TCATCGACGGCTTCGGCGCCCGGCGCATGGGCCGCGGCGCCGCCGCACGCGCCCGCGTCCAGACCCTCACCCCGCGCGAA
CGCGAGGTCCTCGGCCTGGTCGGCGCGGGCCTTTCCAACCCGGAGATCGCCGCCCGCCTGCACCTCGTGGAGGGCACGGT
CAAGGCGTATGTGAGCGCGGTCCTCGAACGGCTCGAAGTCAAGAACCGCGTCCAGGCGGCGATCGTCGCGTACGAGGCGG
GGCTCGTCCCGGAAGCGGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-115)

Bacterial regulatory proteins, luxR family (GerE)

(154-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.615

99.091

0.373
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.368