Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   H7677_RS04325 Genome accession   NZ_AP023391
Coordinates   869539..870918 (+) Length   459 a.a.
NCBI ID   WP_024381361.1    Uniprot ID   A0A075SID2
Organism   Streptococcus suis strain DAT299     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 864539..875918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS04295 (DAT299_08030) pstA 864965..865852 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  H7677_RS04300 (DAT299_08040) pstB 865877..866680 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  H7677_RS04305 (DAT299_08050) pstB 866692..867450 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  H7677_RS04310 (DAT299_08060) phoU 867479..868135 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  H7677_RS04315 (DAT299_08070) - 868301..868681 (+) 381 WP_184494264.1 hypothetical protein -
  H7677_RS04320 (DAT299_08080) ciaR 868875..869546 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  H7677_RS04325 (DAT299_08090) ciaH 869539..870918 (+) 1380 WP_024381361.1 sensor histidine kinase Regulator
  H7677_RS04330 (DAT299_08100) - 871242..872471 (+) 1230 WP_002935288.1 transglutaminase domain-containing protein -
  H7677_RS04335 (DAT299_08110) rpsT 872734..872982 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  H7677_RS04340 (DAT299_08120) coaA 873041..873961 (-) 921 WP_002935283.1 type I pantothenate kinase -
  H7677_RS04345 (DAT299_08130) - 874070..874660 (+) 591 WP_023369994.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51961.70 Da        Isoelectric Point: 6.8882

>NTDB_id=82899 H7677_RS04325 WP_024381361.1 869539..870918(+) (ciaH) [Streptococcus suis strain DAT299]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=82899 H7677_RS04325 WP_024381361.1 869539..870918(+) (ciaH) [Streptococcus suis strain DAT299]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SID2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae D39

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae R6

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.345

99.782

0.492
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488

Multiple sequence alignment