Detailed information NTG0082766

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H7675_RS00675
• Genome accession: NZ_AP023389
• Coordinates: 104546..104980 (+)
• Length: 144 a.a.
• NCBI ID: WP_111711329.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain KUN-0012590
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99546..109980

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7675_RS00645 (KUN2590_00810)	-	101215..101580 (+)	366	WP_002986560.1	DUF1033 family protein	-
H7675_RS00650 (KUN2590_00820)	comYA	101673..102611 (+)	939	WP_184004775.1	competence type IV pilus ATPase ComGA	Machinery gene
H7675_RS00655 (KUN2590_00830)	comYB	102547..103581 (+)	1035	WP_232087598.1	competence type IV pilus assembly protein ComGB	Machinery gene
H7675_RS00660 (KUN2590_00840)	comYC	103583..103909 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
H7675_RS00665 (KUN2590_00850)	comGD	103884..104312 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
H7675_RS00670 (KUN2590_00860)	comGE	104269..104553 (+)	285	WP_011284422.1	competence type IV pilus minor pilin ComGE	-
H7675_RS00675 (KUN2590_00870)	comYF	104546..104980 (+)	435	WP_111711329.1	competence type IV pilus minor pilin ComGF	Machinery gene
H7675_RS00680 (KUN2590_00880)	comGG	104964..105290 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
H7675_RS00685 (KUN2590_00890)	comYH	105388..106341 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
H7675_RS00690 (KUN2590_00900)	-	106400..107596 (+)	1197	WP_111711330.1	acetate kinase	-
H7675_RS00695 (KUN2590_00910)	-	107783..108091 (+)	309	WP_011284425.1	hypothetical protein	-
H7675_RS00700 (KUN2590_00920)	proC	108174..108944 (-)	771	WP_011284426.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16626.22 Da
• Isoelectric Point: 10.1406

>NTDB_id=82766 H7675_RS00675 WP_111711329.1 104546..104980(+) (comYF) [Streptococcus pyogenes strain KUN-0012590]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLAHHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=82766 H7675_RS00675 WP_111711329.1 104546..104980(+) (comYF) [Streptococcus pyogenes strain KUN-0012590]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCATCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (42-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396