Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   R8625_RS00115 Genome accession   NZ_AP026923
Coordinates   21496..21732 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 16496..26732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS00105 (PC0054_00150) - 20224..20620 (+) 397 Protein_14 IS630 family transposase -
  R8625_RS00110 - 20756..21230 (-) 475 Protein_15 hypothetical protein -
  R8625_RS00115 (PC0054_00170) comW 21496..21732 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  R8625_RS00120 (PC0054_00180) - 21963..23249 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  R8625_RS00125 (PC0054_00190) tadA 23450..23917 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  R8625_RS00135 (PC0054_00200) - 24104..24547 (+) 444 WP_000701992.1 dUTP diphosphatase -
  R8625_RS00140 (PC0054_00210) - 24549..25064 (+) 516 WP_001823418.1 histidine phosphatase family protein -
  R8625_RS00145 (PC0054_00220) radA 25078..26439 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=82385 R8625_RS00115 WP_000939546.1 21496..21732(+) (comW) [Streptococcus pneumoniae strain PZ900700054]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=82385 R8625_RS00115 WP_000939546.1 21496..21732(+) (comW) [Streptococcus pneumoniae strain PZ900700054]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756


Multiple sequence alignment