Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QH638_RS04500 Genome accession   NZ_CP123958
Coordinates   872616..873764 (-) Length   382 a.a.
NCBI ID   WP_006248764.1    Uniprot ID   A0A547ELA4
Organism   Mannheimia haemolytica strain 190176     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 867616..878764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QH638_RS04470 rplK 867884..868312 (-) 429 WP_006248758.1 50S ribosomal protein L11 -
  QH638_RS04475 nusG 868545..869108 (-) 564 WP_006248760.1 transcription termination/antitermination protein NusG -
  QH638_RS04480 secE 869110..869523 (-) 414 WP_006248761.1 preprotein translocase subunit SecE -
  QH638_RS04485 - 869636..870658 (-) 1023 WP_006248762.1 LacI family DNA-binding transcriptional regulator -
  QH638_RS04490 - 870889..871158 (+) 270 WP_006248763.1 PTS sugar transporter subunit IIB -
  QH638_RS04495 - 871171..872521 (+) 1351 Protein_859 PTS ascorbate transporter subunit IIC -
  QH638_RS04500 dprA 872616..873764 (-) 1149 WP_006248764.1 DNA-processing protein DprA Machinery gene
  QH638_RS04505 def 873853..874365 (+) 513 WP_006248765.1 peptide deformylase -
  QH638_RS04510 rfaD 874459..875385 (+) 927 WP_006248766.1 ADP-glyceromanno-heptose 6-epimerase -
  QH638_RS04515 fabA 875453..875983 (-) 531 WP_006248767.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  QH638_RS04520 - 876096..877733 (-) 1638 WP_006248768.1 AAA family ATPase -
  QH638_RS04525 matP 877826..878272 (+) 447 WP_006248769.1 macrodomain Ter protein MatP -

Sequence

Protein


Download         Length: 382 a.a.        Molecular weight: 42497.83 Da        Isoelectric Point: 5.2272

>NTDB_id=823254 QH638_RS04500 WP_006248764.1 872616..873764(-) (dprA) [Mannheimia haemolytica strain 190176]
MAYHYDLLRLLQVPQMGAQRIGRLLAELNFAEFCHYDKLQLKQIGWNEKQIQRWFNPDQKWIDQAMTWSELPNQQIVTLF
DENYPFLLKQISTAPPLIYVKGNVESLSLPQIAIVGSRDYSHYGEYWAGQFAAELARHNIIITSGLAIGIDGFAHQKIVM
EQGITIAVLGSGLNQVYPARHKKLAEQIVDLGGALVSEFSPNQPPVAENFPRRNRIISGLSLGTLVIEATLNSGSLITAR
YALEQGREVFALPNAVQNPYAQGCHKLIKEGALLVEGVEDILEVVASQYQPQQIPLFDESKPTVSTSLQAVKNSEKFAKN
LPSLTACQQQIYQHISLEPMAIDDLAKVTELTIEILLVELLGLELAGVIKQVSGGYVMDNGY

Nucleotide


Download         Length: 1149 bp        

>NTDB_id=823254 QH638_RS04500 WP_006248764.1 872616..873764(-) (dprA) [Mannheimia haemolytica strain 190176]
ATGGCATATCACTACGATTTATTACGATTATTACAAGTGCCGCAAATGGGGGCTCAACGTATAGGGCGATTATTGGCGGA
ACTCAATTTTGCTGAATTTTGCCACTATGACAAACTTCAACTCAAACAAATAGGTTGGAATGAAAAGCAAATTCAACGTT
GGTTTAATCCTGATCAAAAGTGGATTGATCAGGCGATGACTTGGTCAGAATTGCCAAATCAGCAAATTGTGACACTCTTT
GATGAAAATTATCCGTTTCTCTTAAAACAAATTTCGACTGCGCCACCGTTAATTTATGTAAAGGGAAATGTGGAAAGCCT
TTCTCTGCCACAAATTGCGATTGTTGGCAGCCGAGACTATTCTCATTATGGTGAATATTGGGCTGGGCAATTTGCTGCCG
AATTAGCTCGCCATAATATTATCATTACCAGCGGTTTAGCCATTGGTATTGACGGTTTTGCCCATCAAAAAATCGTTATG
GAACAAGGCATAACGATTGCCGTGTTAGGGAGTGGATTAAATCAAGTCTATCCTGCTCGCCATAAAAAATTAGCCGAACA
AATTGTTGATTTAGGTGGTGCATTGGTGTCGGAGTTCTCGCCTAATCAGCCGCCGGTGGCAGAAAATTTTCCTCGTCGTA
ATCGAATTATTAGTGGCTTATCGCTCGGCACTTTAGTTATTGAAGCAACGCTTAATAGTGGTTCACTGATTACCGCTCGT
TATGCCCTTGAACAAGGTAGGGAAGTGTTTGCGTTACCGAATGCGGTACAAAACCCTTACGCACAAGGTTGCCACAAGCT
AATTAAAGAAGGGGCATTGCTCGTGGAAGGTGTGGAAGATATTTTAGAGGTGGTCGCCTCGCAATATCAACCTCAGCAAA
TCCCTTTGTTTGATGAGTCTAAGCCAACAGTAAGCACATCTTTACAAGCGGTCAAAAACAGCGAAAAATTCGCAAAAAAT
CTGCCAAGTCTGACCGCTTGCCAGCAGCAAATTTATCAGCATATCAGCTTAGAGCCGATGGCAATTGATGATTTAGCCAA
AGTTACGGAGTTGACGATTGAAATATTGCTGGTTGAATTACTGGGTCTGGAATTAGCCGGTGTGATTAAACAAGTGAGTG
GGGGGTATGTGATGGATAATGGGTATTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-275)

DprA winged helix domain (DprA_WH)

(317-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A547ELA4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

73.615

99.215

0.73
  dprA Haemophilus influenzae Rd KW20

51.304

90.314

0.463
  dprA Vibrio campbellii strain DS40M4

44.744

97.12

0.435
  dprA Vibrio cholerae strain A1552

42.588

97.12

0.414
  dprA Legionella pneumophila strain ERS1305867

40.29

90.314

0.364