Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   R6U80_RS01945 Genome accession   NZ_CP137623
Coordinates   386970..388412 (-) Length   480 a.a.
NCBI ID   WP_012897229.1    Uniprot ID   -
Organism   Lactococcus lactis strain NCK401     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 381970..393412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6U80_RS01920 (R6U80_01920) nox 382005..383345 (+) 1341 WP_023188995.1 H2O-forming NADH oxidase -
  R6U80_RS01925 (R6U80_01925) - 383434..383823 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  R6U80_RS01930 (R6U80_01930) groES 383943..384227 (+) 285 WP_003131589.1 co-chaperone GroES -
  R6U80_RS01935 (R6U80_01935) groL 384316..385944 (+) 1629 WP_003131585.1 chaperonin GroEL -
  R6U80_RS01940 (R6U80_01940) vicX 385989..386801 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  R6U80_RS01945 (R6U80_01945) vicK 386970..388412 (-) 1443 WP_012897229.1 cell wall metabolism sensor histidine kinase WalK Regulator
  R6U80_RS01950 (R6U80_01950) yycF 388405..389106 (-) 702 WP_003131580.1 response regulator YycF -
  R6U80_RS01955 (R6U80_01955) tmk 389284..389919 (+) 636 WP_012897230.1 dTMP kinase -
  R6U80_RS01960 (R6U80_01960) - 390051..390911 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  R6U80_RS01965 (R6U80_01965) yaaT 390963..391745 (+) 783 WP_023188991.1 stage 0 sporulation family protein Regulator
  R6U80_RS01970 (R6U80_01970) yabA 391738..392064 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  R6U80_RS01975 (R6U80_01975) rsmI 392064..392939 (+) 876 WP_003131568.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  R6U80_RS01980 (R6U80_01980) - 393016..393207 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54649.12 Da        Isoelectric Point: 4.5889

>NTDB_id=822643 R6U80_RS01945 WP_012897229.1 386970..388412(-) (vicK) [Lactococcus lactis strain NCK401]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=822643 R6U80_RS01945 WP_012897229.1 386970..388412(-) (vicK) [Lactococcus lactis strain NCK401]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGCAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACACTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442