Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   R8566_RS00115 Genome accession   NZ_AP026920
Coordinates   21577..21813 (+) Length   78 a.a.
NCBI ID   WP_000939547.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700014     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 16577..26813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8566_RS00105 - 20283..20492 (+) 210 Protein_14 transposase -
  R8566_RS00110 - 20527..21311 (-) 785 Protein_15 transposase -
  R8566_RS00115 (PC0014_00160) comW 21577..21813 (+) 237 WP_000939547.1 sigma(X)-activator ComW Regulator
  R8566_RS00120 (PC0014_00170) - 22044..23330 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  R8566_RS00125 (PC0014_00180) tadA 23531..23998 (+) 468 WP_000291877.1 tRNA adenosine(34) deaminase TadA -
  R8566_RS00135 (PC0014_00190) - 24207..25343 (-) 1137 WP_224757251.1 site-specific integrase -
  R8566_RS00140 (PC0014_00200) - 25468..25818 (-) 351 WP_001020945.1 hypothetical protein -
  R8566_RS00145 (PC0014_00210) - 25832..26212 (-) 381 WP_000136430.1 ImmA/IrrE family metallo-endopeptidase -
  R8566_RS00150 (PC0014_00220) - 26234..26590 (-) 357 WP_000153672.1 helix-turn-helix domain-containing protein -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9688.15 Da        Isoelectric Point: 6.7051

>NTDB_id=82028 R8566_RS00115 WP_000939547.1 21577..21813(+) (comW) [Streptococcus pneumoniae strain PZ900700014]
MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=82028 R8566_RS00115 WP_000939547.1 21577..21813(+) (comW) [Streptococcus pneumoniae strain PZ900700014]
ATGTTACAAAAAATTTATGAGCAGATGACTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

75.641

100

0.756

  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744


Multiple sequence alignment