Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   R4707_RS05915 Genome accession   NZ_CP137113
Coordinates   1111078..1111314 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain ZGX     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1106078..1116314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS05910 - 1109999..1110812 (-) 814 Protein_1112 transposase -
  R4707_RS05915 comW 1111078..1111314 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  R4707_RS05920 - 1111545..1112831 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  R4707_RS05925 tadA 1113032..1113499 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  R4707_RS05935 - 1113708..1114844 (-) 1137 WP_257617667.1 site-specific integrase -
  R4707_RS05940 - 1114905..1115975 (-) 1071 WP_000401841.1 type I restriction endonuclease -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=820008 R4707_RS05915 WP_000939545.1 1111078..1111314(+) (comW) [Streptococcus pneumoniae strain ZGX]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=820008 R4707_RS05915 WP_000939545.1 1111078..1111314(+) (comW) [Streptococcus pneumoniae strain ZGX]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744