Detailed information NTG0819451

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAY80_RS06550
• Genome accession: NZ_CP123142
• Coordinates: 1333214..1334257 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GE-MRSA21
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1328214..1339257

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY80_RS06520 (QAY80_06535)	-	1328635..1329891 (-)	1257	WP_001795108.1	aminopeptidase	-
QAY80_RS06525 (QAY80_06540)	-	1329894..1330094 (-)	201	WP_000180460.1	DUF1128 family protein	-
QAY80_RS06530 (QAY80_06545)	-	1330241..1330705 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAY80_RS06535 (QAY80_06550)	-	1330712..1330987 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QAY80_RS06540 (QAY80_06555)	-	1331265..1332482 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QAY80_RS06545 (QAY80_06560)	vraR	1332595..1333224 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QAY80_RS06550 (QAY80_06565)	vraS	1333214..1334257 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAY80_RS06555 (QAY80_06570)	liaF	1334254..1334955 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAY80_RS06560 (QAY80_06575)	-	1334970..1335356 (-)	387	WP_001110179.1	hypothetical protein	-
QAY80_RS06565 (QAY80_06580)	map	1335573..1336331 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAY80_RS06570 (QAY80_06585)	-	1336862..1337848 (+)	987	WP_000999717.1	FUSC family protein	-
QAY80_RS06575 (QAY80_06590)	-	1338279..1338692 (-)	414	WP_001557448.1	hypothetical protein	-
QAY80_RS06580 (QAY80_06595)	-	1338721..1338831 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=819451 QAY80_RS06550 WP_001017131.1 1333214..1334257(-) (vraS) [Staphylococcus aureus strain GE-MRSA21]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=819451 QAY80_RS06550 WP_001017131.1 1333214..1334257(-) (vraS) [Staphylococcus aureus strain GE-MRSA21]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1