Detailed information NTG0819004

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY61_RS14155
• Genome accession: NZ_CP123115
• Coordinates: 2825254..2826141 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IT-MRSA43
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2820254..2831141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY61_RS14125 (QAY61_14100)	-	2820272..2820360 (+)	89	Protein_2742	hypothetical protein	-
QAY61_RS14130 (QAY61_14105)	-	2820468..2820965 (-)	498	WP_001065267.1	glutathione peroxidase	-
QAY61_RS14135 (QAY61_14110)	-	2820975..2821235 (-)	261	WP_072434822.1	hypothetical protein	-
QAY61_RS14140 (QAY61_14115)	-	2821617..2821730 (-)	114	WP_072384844.1	hypothetical protein	-
QAY61_RS14145 (QAY61_14120)	-	2822394..2824394 (-)	2001	WP_000776746.1	ABC transporter permease	-
QAY61_RS14150 (QAY61_14125)	-	2824391..2825146 (-)	756	WP_001670202.1	ABC transporter ATP-binding protein	-
QAY61_RS14155 (QAY61_14130)	braS	2825254..2826141 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY61_RS14160 (QAY61_14135)	braR	2826152..2826817 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY61_RS14165 (QAY61_14140)	-	2826843..2827043 (-)	201	WP_000604723.1	hypothetical protein	-
QAY61_RS14170 (QAY61_14145)	-	2827241..2828665 (+)	1425	WP_000953731.1	alkaline phosphatase	-
QAY61_RS14175	-	2828725..2828826 (-)	102	WP_000731972.1	SE2200 family small protein	-
QAY61_RS14180 (QAY61_14155)	-	2828948..2829403 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY61_RS14185 (QAY61_14160)	-	2829649..2830410 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=819004 QAY61_RS14155 WP_000143420.1 2825254..2826141(-) (braS) [Staphylococcus aureus strain IT-MRSA43]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819004 QAY61_RS14155 WP_000143420.1 2825254..2826141(-) (braS) [Staphylococcus aureus strain IT-MRSA43]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993