Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   R4708_RS05115 Genome accession   NZ_CP137104
Coordinates   1028225..1028461 (-) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LM     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 1023225..1033461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS05085 radA 1023518..1024879 (-) 1362 WP_073076903.1 DNA repair protein RadA Machinery gene
  R4708_RS05090 - 1024893..1025408 (-) 516 WP_000691236.1 histidine phosphatase family protein -
  R4708_RS05095 - 1025410..1025853 (-) 444 WP_000701992.1 dUTP diphosphatase -
  R4708_RS05105 tadA 1026040..1026507 (-) 468 WP_000291879.1 tRNA adenosine(34) deaminase TadA -
  R4708_RS05110 - 1026708..1027994 (-) 1287 WP_000205044.1 adenylosuccinate synthase -
  R4708_RS05115 comW 1028225..1028461 (-) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  R4708_RS05120 - 1028727..1029524 (+) 798 Protein_1019 transposase -
  R4708_RS05125 - 1029559..1029768 (-) 210 Protein_1020 transposase -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=818905 R4708_RS05115 WP_000939544.1 1028225..1028461(-) (comW) [Streptococcus pneumoniae strain LM]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=818905 R4708_RS05115 WP_000939544.1 1028225..1028461(-) (comW) [Streptococcus pneumoniae strain LM]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974

  comW Streptococcus pneumoniae D39

97.436

100

0.974

  comW Streptococcus pneumoniae R6

97.436

100

0.974

  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974

  comW Streptococcus mitis SK321

78.205

100

0.782

  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769