Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   R4709_RS05325 Genome accession   NZ_CP137102
Coordinates   1031850..1032086 (-) Length   78 a.a.
NCBI ID   WP_050233459.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H3071-2     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1026850..1037086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4709_RS05295 - 1026863..1027072 (-) 210 WP_000082680.1 helix-turn-helix transcriptional regulator -
  R4709_RS05300 - 1027359..1027724 (+) 366 WP_000477680.1 helix-turn-helix domain-containing protein -
  R4709_RS05305 - 1027737..1028120 (+) 384 WP_000136458.1 ImmA/IrrE family metallo-endopeptidase -
  R4709_RS05310 - 1028165..1028572 (+) 408 WP_001173135.1 DUF4429 domain-containing protein -
  R4709_RS05315 - 1028943..1030091 (+) 1149 WP_000876722.1 site-specific integrase -
  R4709_RS05320 - 1030333..1031619 (-) 1287 WP_000205044.1 adenylosuccinate synthase -
  R4709_RS05325 comW 1031850..1032086 (-) 237 WP_050233459.1 sigma(X)-activator ComW Regulator
  R4709_RS05330 - 1032352..1033149 (+) 798 Protein_1060 transposase -
  R4709_RS05335 - 1033184..1034022 (-) 839 Protein_1061 IS630 family transposase -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9648.09 Da        Isoelectric Point: 6.7051

>NTDB_id=818672 R4709_RS05325 WP_050233459.1 1031850..1032086(-) (comW) [Streptococcus pneumoniae strain 16H3071-2]
MLQKIYEQMANFYDSIEEEYGSTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=818672 R4709_RS05325 WP_050233459.1 1031850..1032086(-) (comW) [Streptococcus pneumoniae strain 16H3071-2]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTTCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987
  comW Streptococcus pneumoniae D39

98.718

100

0.987
  comW Streptococcus pneumoniae R6

98.718

100

0.987
  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744