NTDB

Overview

Name	comR	Type	Regulator
Locus tag	R1Y14_RS00470	Genome accession	NZ_CP136899
Coordinates	76662..77483 (-)	Length	273 a.a.
NCBI ID	WP_000904827.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain ST62
Function	activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 71662..82483

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R1Y14_RS00445 (R1Y14_00445)	rsmA	71887..72759 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
R1Y14_RS00450 (R1Y14_00450)	-	73010..73303 (-)	294	WP_000333255.1	hypothetical protein	-
R1Y14_RS00455 (R1Y14_00455)	-	73296..73937 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
R1Y14_RS00460 (R1Y14_00460)	-	73939..75969 (-)	2031	WP_054366032.1	bacteriocin-associated integral membrane family protein	-
R1Y14_RS00465 (R1Y14_00465)	-	76046..76342 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
R1Y14_RS00470 (R1Y14_00470)	comR	76662..77483 (-)	822	WP_000904827.1	XRE family transcriptional regulator	Regulator
R1Y14_RS00475 (R1Y14_00475)	rnmV	77555..78115 (-)	561	WP_000660019.1	ribonuclease M5	-
R1Y14_RS00480 (R1Y14_00480)	-	78115..78888 (-)	774	WP_000575601.1	TatD family hydrolase	-
R1Y14_RS00485 (R1Y14_00485)	-	79193..79912 (-)	720	Protein_81	DUF1542 domain-containing protein	-
R1Y14_RS00490 (R1Y14_00490)	rpmH	80121..80255 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
R1Y14_RS00495 (R1Y14_00495)	-	80400..81614 (-)	1215	WP_000666472.1	pyridoxal phosphate-dependent aminotransferase	-
R1Y14_RS00500 (R1Y14_00500)	-	81770..82063 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

Download Length: 273 a.a. Molecular weight: 32180.61 Da Isoelectric Point: 6.1110

                                >NTDB_id=815985 R1Y14_RS00470 WP_000904827.1 76662..77483(-) (comR) [Streptococcus pneumoniae strain ST62]

MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI

LREPIYGKEEEYDKKEACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLLIRLFFYQMLIRKDLAKFINQIEKLML

FLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAES

FYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

Download Length: 822 bp

                                >NTDB_id=815985 R1Y14_RS00470 WP_000904827.1 76662..77483(-) (comR) [Streptococcus pneumoniae strain ST62]

ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA

ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC

GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT

TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTATGATAAGAAAGAAGCGTGTTTGGATACTTCTAGAACTAGAAGGCC

TGAATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGT

TGATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTC

TTTCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTG

TCTTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATT

ATCAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCA

TTTTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGA

GGATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(7-59)

ComR tetratricopeptide (ComR_TPR)

(94-265)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comR	Streptococcus pyogenes MGAS8232	34.564	100	0.377
comR	Streptococcus mutans UA159	34.354	100	0.37
comR	Streptococcus suis P1/7	34.364	100	0.366
comR	Streptococcus suis 05ZYH33	34.364	100	0.366
comR	Streptococcus pyogenes MGAS315	33.333	100	0.366

Detailed information NTG0815985