Detailed information NTG0081580

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: HSX14_RS09260
• Genome accession: NZ_AP023189
• Coordinates: 2003040..2005262 (+)
• Length: 740 a.a.
• NCBI ID: WP_228723564.1
• Uniprot ID: A0A6J4E3V0
• Organism: Pseudomonas tohonis strain TUM18999
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1998040..2010262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSX14_RS09230 (TUM18999_18290)	-	1998125..1998418 (-)	294	WP_111262764.1	phosphodiesterase	-
HSX14_RS09235 (TUM18999_18300)	-	1998423..1999010 (-)	588	WP_173173789.1	PilZ domain-containing protein	-
HSX14_RS09240 (TUM18999_18310)	-	1999107..2000357 (+)	1251	WP_173173791.1	lipoprotein-releasing ABC transporter permease subunit	-
HSX14_RS09245 (TUM18999_18320)	lolD	2000359..2001042 (+)	684	WP_173174046.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
HSX14_RS09250 (TUM18999_18330)	-	2001044..2002288 (+)	1245	WP_173173793.1	lipoprotein-releasing ABC transporter permease subunit	-
HSX14_RS09255 (TUM18999_18340)	-	2002359..2002889 (-)	531	WP_173173795.1	DUF2062 domain-containing protein	-
HSX14_RS09260 (TUM18999_18350)	comA	2003040..2005262 (+)	2223	WP_228723564.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HSX14_RS09265 (TUM18999_18360)	exbB	2005335..2005970 (+)	636	WP_173173797.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
HSX14_RS09270 (TUM18999_18370)	-	2005967..2006410 (+)	444	WP_173173799.1	ExbD/TolR family protein	-
HSX14_RS09275 (TUM18999_18380)	lpxK	2006410..2007414 (+)	1005	WP_173173801.1	tetraacyldisaccharide 4'-kinase	-
HSX14_RS09280 (TUM18999_18390)	-	2007456..2007641 (+)	186	WP_111262773.1	Trm112 family protein	-
HSX14_RS09285 (TUM18999_18400)	kdsB	2007641..2008405 (+)	765	WP_173173803.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
HSX14_RS09290 (TUM18999_18410)	-	2008405..2008863 (+)	459	WP_173173805.1	low molecular weight protein-tyrosine-phosphatase	-
HSX14_RS09295 (TUM18999_18420)	murB	2008860..2009879 (+)	1020	WP_173173807.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 78991.46 Da
• Isoelectric Point: 10.3232

>NTDB_id=81580 HSX14_RS09260 WP_228723564.1 2003040..2005262(+) (comA) [Pseudomonas tohonis strain TUM18999]
MTWALVALGGGLAAVRFMPALPPTAWLLAAAALGLALLAGRGRAPGLFLLGIAWGCCCAQWALDDRLAPSLDGETRWLEG
RVVGLPQRGSGVVRFELDDPQMPGAELPSRIRLSWYGGPQLRGGERWRLAVTLKRPRGLVNPHAFDYEAWLLARHIGASG
SVKAGKPLAPGNGPAAWRDRLRQGIEQVPAHGRNGGIAALVLGDGSGLVAADWRLLQDTGTVHLMVISGQHIALLAAVLY
GAVALLARLGLWPGRLPWLPCACALAFVGSLGYGLLAGFDVPVQRACLMTAIALLWRLRFRHLGVVRPLLVAFCVVLAAD
PLASLQAGFWLSFGAVALLILIFAGRMGVPPWWLSWWRAQWTMGLALSPLLLALALPISLSGPLANLVAVPWVSLVSVPL
SLLGTALQGVPWLGAGLLWLAGGSLELLFRLLAWIAAWVPAWQATAVPPWAWLLGMGGCLLLVLPAGVPVRVLGVALLLP
TLFPPVERPPWGRADIWLLDVGQGLSVLVRTREHALLYDTGARRGDFDMGERVVLPSLLGLGVRQLDQLLLSHADNDHAG
GAGAVLRGMPVTRVVSGEPLRLPAALGATACGNQAWEWDGVRLRTWRWEQARSGNDRSCVLSVEAHGERIHLTGDIGVQA
EAAWIASGEPLRADWLLAPHHGSASSSSAALIEAVSPRGALITRGSHNAFGHPHPSVVARYRASGVAIHDTAQSGALLIR
LGERDEVRGLRTQARFWREK

Nucleotide

• Length: 2223 bp

>NTDB_id=81580 HSX14_RS09260 WP_228723564.1 2003040..2005262(+) (comA) [Pseudomonas tohonis strain TUM18999]
ATGACGTGGGCGTTGGTGGCGCTGGGCGGTGGCCTGGCTGCGGTGCGGTTCATGCCGGCGTTGCCGCCGACCGCCTGGCT
GCTCGCGGCGGCGGCACTGGGGCTGGCATTGCTGGCCGGGCGCGGGCGGGCGCCCGGTCTGTTCCTGCTGGGGATCGCCT
GGGGCTGCTGCTGCGCCCAATGGGCCCTGGATGATCGGCTGGCCCCATCCCTCGATGGCGAGACCCGCTGGCTGGAGGGG
CGGGTCGTCGGGCTGCCGCAACGGGGCAGCGGGGTGGTGCGCTTCGAGTTGGACGATCCGCAGATGCCAGGTGCCGAACT
GCCGTCGCGTATCCGCCTGTCCTGGTACGGCGGGCCACAGCTGCGCGGCGGGGAGCGCTGGCGCCTGGCCGTGACCCTCA
AGCGCCCGCGCGGCCTGGTCAATCCGCATGCCTTCGATTACGAAGCCTGGCTCCTTGCCCGGCACATAGGCGCCAGCGGT
TCGGTGAAGGCCGGCAAGCCGTTGGCGCCGGGCAATGGCCCCGCCGCCTGGCGTGACCGCCTGCGCCAGGGCATCGAGCA
GGTGCCGGCCCATGGGCGCAACGGCGGCATCGCGGCGTTGGTACTGGGCGATGGCTCGGGACTGGTCGCTGCCGACTGGC
GCTTGCTTCAGGACACGGGGACCGTGCACCTGATGGTGATCTCCGGCCAGCACATCGCCTTGCTCGCCGCCGTGCTCTAC
GGCGCCGTCGCGCTGCTGGCGCGGCTCGGTCTCTGGCCCGGACGCCTGCCCTGGTTGCCCTGCGCCTGTGCCCTGGCGTT
CGTCGGATCGCTGGGCTACGGCTTGCTGGCCGGCTTCGACGTGCCGGTGCAGCGCGCTTGCCTGATGACCGCCATCGCGC
TGCTCTGGCGCCTGCGTTTCCGCCACCTCGGGGTGGTCCGCCCGTTGCTGGTGGCCTTCTGCGTGGTGCTGGCGGCGGAC
CCGCTGGCCTCCCTGCAGGCAGGATTCTGGTTGTCCTTCGGCGCCGTGGCGTTGCTCATCCTGATCTTCGCGGGGCGGAT
GGGCGTGCCACCCTGGTGGCTCAGCTGGTGGCGCGCGCAATGGACCATGGGGTTGGCGCTGTCACCCTTGCTGCTGGCGT
TGGCACTGCCCATCAGCCTGAGTGGCCCGCTGGCCAACCTGGTCGCCGTGCCCTGGGTCAGCCTGGTCTCGGTGCCGCTG
TCCCTGCTCGGGACTGCGCTGCAGGGCGTGCCCTGGCTGGGCGCAGGGCTGCTGTGGCTGGCCGGCGGTTCGCTGGAGCT
GTTGTTCCGGCTGCTGGCCTGGATCGCCGCGTGGGTCCCGGCCTGGCAAGCGACGGCCGTTCCTCCGTGGGCCTGGCTGC
TGGGCATGGGCGGCTGCCTGTTGCTGGTTCTTCCGGCGGGCGTGCCGGTGCGTGTCCTGGGCGTGGCGCTGCTGTTGCCG
ACGTTGTTTCCCCCCGTGGAGCGGCCGCCCTGGGGGAGGGCGGACATCTGGCTGCTGGATGTCGGGCAGGGATTGTCGGT
GCTGGTGCGGACCCGGGAGCACGCGCTGCTCTACGACACGGGCGCCCGGCGCGGCGACTTCGACATGGGCGAGCGGGTGG
TGCTACCGAGCCTGTTGGGGCTGGGGGTGCGGCAGCTGGACCAGTTGCTGCTCAGCCATGCCGACAACGACCACGCCGGC
GGTGCCGGAGCGGTACTGCGTGGCATGCCGGTGACGCGGGTGGTCAGCGGTGAGCCGCTGCGCCTGCCGGCTGCGCTGGG
CGCCACGGCCTGTGGCAACCAAGCGTGGGAGTGGGATGGCGTGCGCCTGCGTACCTGGCGCTGGGAGCAGGCGCGCAGTG
GCAACGACCGGTCCTGTGTGCTCAGCGTCGAGGCGCACGGCGAGCGCATCCACCTGACCGGCGACATCGGTGTCCAGGCC
GAGGCCGCCTGGATCGCCAGCGGTGAACCCCTGCGCGCCGACTGGCTGCTGGCACCGCACCACGGCAGTGCCAGCTCCTC
CTCCGCGGCGCTGATCGAGGCGGTGTCGCCCCGTGGTGCGTTGATCACCCGGGGCAGCCACAACGCCTTCGGTCATCCGC
ATCCGTCCGTCGTCGCCCGCTACCGTGCCTCTGGCGTCGCGATCCATGACACGGCGCAGTCCGGTGCGCTGCTGATCCGT
CTCGGCGAACGTGACGAGGTGCGTGGACTGCGGACCCAGGCACGTTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (500-682)

• Domain of unknown function (DUF4131) (DUF4131) (19-165)

• Competence protein (Competence) (200-465)

3D structure

• AlphaFold DB: A0A6J4E3V0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	64.444	97.297	0.627
comA	Ralstonia pseudosolanacearum GMI1000	36.375	100	0.382