Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R1Y80_RS05095 Genome accession   NZ_CP136798
Coordinates   1160316..1160936 (+) Length   206 a.a.
NCBI ID   WP_032780914.1    Uniprot ID   -
Organism   Streptomyces sp. JL1001     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1155316..1165936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y80_RS05075 (R1Y80_05060) - 1156646..1157284 (-) 639 WP_032768150.1 vitamin K epoxide reductase family protein -
  R1Y80_RS05080 (R1Y80_05065) - 1157421..1158278 (+) 858 WP_106969631.1 ABC transporter ATP-binding protein -
  R1Y80_RS05085 (R1Y80_05070) - 1158275..1159096 (+) 822 WP_354596500.1 ABC transporter permease -
  R1Y80_RS05090 (R1Y80_05075) - 1159054..1160316 (+) 1263 WP_354596501.1 sensor histidine kinase -
  R1Y80_RS05095 (R1Y80_05080) vraR 1160316..1160936 (+) 621 WP_032780914.1 response regulator transcription factor Regulator
  R1Y80_RS05100 (R1Y80_05085) hisS 1161003..1162265 (-) 1263 WP_100562277.1 histidine--tRNA ligase -
  R1Y80_RS05105 (R1Y80_05090) - 1162283..1162972 (-) 690 WP_032768143.1 MBL fold metallo-hydrolase -
  R1Y80_RS05110 (R1Y80_05095) - 1163130..1163921 (+) 792 WP_354596502.1 peptidylprolyl isomerase -
  R1Y80_RS05115 (R1Y80_05100) - 1164146..1165375 (+) 1230 WP_354596503.1 DUF349 domain-containing protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21922.42 Da        Isoelectric Point: 5.7852

>NTDB_id=815535 R1Y80_RS05095 WP_032780914.1 1160316..1160936(+) (vraR) [Streptomyces sp. JL1001]
MIRVLLADDHPVVREGLRGMLDAEADLDVVGEADSGPRAEALCAELLPDIVLMDLRMPGGGGVESIRRIRAAGLPCRVVV
LTTYESDGDILRAVEAGASGYLLKDLGRGELADAIRAAARGETVLAPTVATRLVDRLRGVPELPRLSERETQVLRLVAEG
CTNAEIGRKLFIGESTVKTHLLRIFGKLGVGDRTAAVTGAMRHGLL

Nucleotide


Download         Length: 621 bp        

>NTDB_id=815535 R1Y80_RS05095 WP_032780914.1 1160316..1160936(+) (vraR) [Streptomyces sp. JL1001]
ATGATCCGTGTCCTGCTGGCCGACGACCACCCCGTCGTACGGGAGGGGCTGCGCGGAATGCTGGACGCCGAGGCCGACCT
CGACGTGGTGGGCGAGGCCGACAGCGGCCCCCGTGCCGAGGCCCTGTGCGCCGAGCTGCTGCCGGACATCGTGCTGATGG
ACCTGCGGATGCCGGGCGGCGGGGGCGTCGAGTCGATCCGCCGGATACGGGCGGCGGGGCTGCCGTGCCGGGTCGTGGTG
CTGACCACGTACGAGAGCGACGGCGACATCCTGCGGGCGGTGGAGGCCGGGGCGTCCGGCTATCTGCTCAAGGACCTGGG
CCGGGGCGAGCTGGCGGACGCGATCCGGGCCGCGGCGCGGGGCGAGACGGTGCTCGCGCCGACGGTGGCGACCCGGCTGG
TGGACCGGCTGCGCGGGGTGCCGGAGCTGCCGCGGCTCTCGGAGCGGGAGACGCAGGTGCTGCGGCTGGTGGCGGAGGGG
TGCACCAATGCGGAGATCGGGCGGAAGCTGTTCATCGGGGAGTCGACGGTGAAGACCCATCTGCTGCGGATCTTCGGCAA
GCTGGGCGTCGGCGACCGTACGGCGGCGGTGACGGGGGCGATGCGCCACGGGCTGCTGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-198)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.262

100

0.413
  degU Bacillus subtilis subsp. subtilis str. 168

34.978

100

0.379
  letA Legionella pneumophila str. Paris

36.842

100

0.374
  letA Legionella pneumophila strain ERS1305867

36.842

100

0.374