Detailed information NTG0081368

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R8474_RS05600
• Genome accession: NZ_AP026914
• Coordinates: 1108103..1109056 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain PZ900700003
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1103103..1114056

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8474_RS05575	-	1103594..1103689 (-)	96	Protein_1102	IS630 family transposase	-
R8474_RS05580 (PC0003_11110)	-	1104101..1104442 (+)	342	Protein_1103	transposase	-
R8474_RS05585 (PC0003_11120)	prsA	1104559..1105500 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R8474_RS05590 (PC0003_11130)	-	1105567..1106280 (-)	714	WP_000230399.1	O-methyltransferase	-
R8474_RS05595 (PC0003_11140)	pepF	1106282..1108084 (-)	1803	WP_000244130.1	oligoendopeptidase F	Regulator
R8474_RS05600 (PC0003_11150)	coiA	1108103..1109056 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R8474_RS05605 (PC0003_11160)	tehB	1109129..1109989 (-)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
R8474_RS05610 (PC0003_11170)	smpB	1110005..1110472 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R8474_RS05615 (PC0003_11180)	rnr	1110435..1112789 (-)	2355	WP_000654908.1	ribonuclease R	-
R8474_RS05620 (PC0003_11190)	secG	1112891..1113124 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R8474_RS05625	rpmG	1113164..1113313 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=81368 R8474_RS05600 WP_000495909.1 1108103..1109056(-) (coiA) [Streptococcus pneumoniae strain PZ900700003]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=81368 R8474_RS05600 WP_000495909.1 1108103..1109056(-) (coiA) [Streptococcus pneumoniae strain PZ900700003]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterProScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435