Detailed information NTG0812868

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: QA712_RS06870
• Genome accession: NZ_CP121539
• Coordinates: 1249841..1250287 (-)
• Length: 148 a.a.
• NCBI ID: WP_195935889.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain MA5
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1244841..1255287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QA712_RS06835 (QA712_06835)	-	1244959..1245336 (-)	378	WP_003129983.1	pyridoxamine 5'-phosphate oxidase family protein	-
QA712_RS06840 (QA712_06840)	-	1245541..1246407 (+)	867	WP_332529355.1	RluA family pseudouridine synthase	-
QA712_RS06845 (QA712_06845)	-	1246445..1247254 (-)	810	WP_014570791.1	metal ABC transporter permease	-
QA712_RS06850 (QA712_06850)	-	1247247..1247984 (-)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
QA712_RS06855 (QA712_06855)	-	1248161..1249003 (-)	843	WP_311920327.1	metal ABC transporter substrate-binding protein	-
QA712_RS06860 (QA712_06860)	-	1249000..1249437 (-)	438	WP_010906313.1	zinc-dependent MarR family transcriptional regulator	-
QA712_RS06865 (QA712_06865)	comGG	1249518..1249802 (-)	285	WP_311802844.1	competence type IV pilus minor pilin ComGG	Machinery gene
QA712_RS06870 (QA712_06870)	comGF	1249841..1250287 (-)	447	WP_195935889.1	competence type IV pilus minor pilin ComGF	Machinery gene
QA712_RS06875 (QA712_06875)	comGE	1250250..1250546 (-)	297	WP_332529356.1	competence type IV pilus minor pilin ComGE	Machinery gene
QA712_RS06880 (QA712_06880)	comGD	1250518..1250949 (-)	432	WP_195935890.1	competence type IV pilus minor pilin ComGD	Machinery gene
QA712_RS06885 (QA712_06885)	comGC	1250909..1251178 (-)	270	WP_021721869.1	competence type IV pilus major pilin ComGC	Machinery gene
QA712_RS06890 (QA712_06890)	comGB	1251306..1252380 (-)	1075	Protein_1223	competence type IV pilus assembly protein ComGB	-
QA712_RS06895 (QA712_06895)	comGA	1252274..1253212 (-)	939	WP_195935891.1	competence type IV pilus ATPase ComGA	Machinery gene
QA712_RS06900 (QA712_06900)	-	1253481..1253663 (-)	183	WP_047206975.1	hypothetical protein	-
QA712_RS06905 (QA712_06905)	-	1253654..1254244 (-)	591	WP_052772651.1	hypothetical protein	-

Sequence

Protein

• Length: 148 a.a.
• Molecular weight: 17112.89 Da
• Isoelectric Point: 8.2376

>NTDB_id=812868 QA712_RS06870 WP_195935889.1 1249841..1250287(-) (comGF) [Lactococcus lactis strain MA5]
MERKLCDLNFKVKAFTLLECLVALLAISGSVLVISGLTKMLKEQVAISQSDSIKDWQIFCQQMRFELSGTKLDRVEQDFL
YVTKDKKLRFGFMSDDFRKTDDKGQGYQPMLYDIKAAKIQATKNLITIRIDFNQGGERTFIYQFPEDT

Nucleotide

• Length: 447 bp

>NTDB_id=812868 QA712_RS06870 WP_195935889.1 1249841..1250287(-) (comGF) [Lactococcus lactis strain MA5]
ATGGAAAGGAAATTATGCGACTTGAACTTCAAAGTTAAAGCATTTACCTTGTTGGAGTGTTTGGTGGCACTTCTTGCAAT
TTCTGGTTCAGTCCTTGTCATCTCAGGTTTAACAAAGATGTTGAAAGAACAAGTGGCGATTAGTCAAAGTGATAGCATAA
AAGATTGGCAAATTTTCTGTCAGCAAATGCGTTTTGAACTCTCAGGAACAAAATTAGATAGGGTAGAACAGGATTTTCTG
TATGTAACTAAAGATAAAAAACTAAGGTTTGGTTTTATGAGTGATGATTTCCGGAAGACTGATGACAAAGGTCAGGGTTA
TCAGCCAATGCTTTATGATATAAAAGCGGCTAAGATTCAAGCTACTAAAAATTTAATAACCATAAGAATTGATTTTAATC
AAGGAGGTGAAAGAACATTTATCTATCAATTTCCAGAAGATACGTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (48-137)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Lactococcus lactis subsp. cremoris KW2	75.54	93.919	0.709
comYF	Streptococcus mutans UA140	47.518	95.27	0.453
comYF	Streptococcus mutans UA159	46.809	95.27	0.446
comGF/cglF	Streptococcus mitis SK321	42.336	92.568	0.392
comGF/cglF	Streptococcus mitis NCTC 12261	42.336	92.568	0.392
comGF/cglF	Streptococcus pneumoniae Rx1	39.716	95.27	0.378
comGF/cglF	Streptococcus pneumoniae D39	39.716	95.27	0.378
comGF/cglF	Streptococcus pneumoniae R6	39.716	95.27	0.378
comGF/cglF	Streptococcus pneumoniae TIGR4	39.716	95.27	0.378