Detailed information
Bioinformatically predicted
Overview
| Name | ciaR | Type | Regulator |
| Locus tag | P7F70_RS05280 | Genome accession | NZ_CP121201 |
| Coordinates | 1038246..1038917 (-) | Length | 223 a.a. |
| NCBI ID | WP_104967889.1 | Uniprot ID | A0A2L0D3Z7 |
| Organism | Streptococcus pluranimalium strain SP28 | ||
| Function | repress competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1015016..1046773 | 1038246..1038917 | within | 0 |
Gene organization within MGE regions
Location: 1015016..1046773
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P7F70_RS05165 (P7F70_05165) | - | 1015016..1016752 (-) | 1737 | WP_104967867.1 | ABC transporter ATP-binding protein | - |
| P7F70_RS05170 (P7F70_05170) | - | 1016749..1018485 (-) | 1737 | WP_218654361.1 | ABC transporter ATP-binding protein | - |
| P7F70_RS05175 (P7F70_05175) | - | 1018503..1019108 (-) | 606 | WP_218654362.1 | lysozyme family protein | - |
| P7F70_RS05180 (P7F70_05180) | - | 1019108..1020082 (-) | 975 | WP_104967870.1 | nucleoid-associated protein | - |
| P7F70_RS05185 (P7F70_05185) | glyA | 1020087..1021343 (-) | 1257 | WP_104968844.1 | serine hydroxymethyltransferase | - |
| P7F70_RS05190 (P7F70_05190) | - | 1021354..1021785 (-) | 432 | WP_278025296.1 | GNAT family N-acetyltransferase | - |
| P7F70_RS05195 (P7F70_05195) | - | 1021798..1022388 (-) | 591 | WP_340655233.1 | L-threonylcarbamoyladenylate synthase | - |
| P7F70_RS05200 (P7F70_05200) | prmC | 1022394..1023221 (-) | 828 | WP_278025298.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| P7F70_RS05205 (P7F70_05205) | prfA | 1023221..1024300 (-) | 1080 | WP_278025299.1 | peptide chain release factor 1 | - |
| P7F70_RS05210 (P7F70_05210) | - | 1024334..1024912 (-) | 579 | WP_104967875.1 | thymidine kinase | - |
| P7F70_RS05215 (P7F70_05215) | - | 1025347..1025532 (+) | 186 | WP_115130289.1 | 4-oxalocrotonate tautomerase | - |
| P7F70_RS05220 (P7F70_05220) | - | 1025541..1026479 (+) | 939 | WP_218654366.1 | FAD:protein FMN transferase | - |
| P7F70_RS05225 (P7F70_05225) | - | 1026528..1026866 (-) | 339 | WP_104967878.1 | ATP cone domain-containing protein | - |
| P7F70_RS05230 (P7F70_05230) | - | 1026997..1028364 (-) | 1368 | WP_115130291.1 | FAD-dependent oxidoreductase | - |
| P7F70_RS05235 (P7F70_05235) | - | 1028745..1029701 (-) | 957 | WP_218654367.1 | ABC transporter permease | - |
| P7F70_RS05240 (P7F70_05240) | - | 1029704..1030765 (-) | 1062 | WP_104967881.1 | ABC transporter permease | - |
| P7F70_RS05245 (P7F70_05245) | - | 1030758..1032290 (-) | 1533 | WP_278025300.1 | ABC transporter ATP-binding protein | - |
| P7F70_RS05250 (P7F70_05250) | - | 1032432..1033481 (-) | 1050 | WP_278025301.1 | BMP family protein | - |
| P7F70_RS05255 (P7F70_05255) | - | 1033554..1033943 (-) | 390 | WP_278025302.1 | cytidine deaminase | - |
| P7F70_RS05260 (P7F70_05260) | - | 1034537..1035124 (-) | 588 | WP_278025303.1 | class I SAM-dependent methyltransferase | - |
| P7F70_RS05265 (P7F70_05265) | coaA | 1035251..1036171 (+) | 921 | WP_218654369.1 | type I pantothenate kinase | - |
| P7F70_RS05270 (P7F70_05270) | rpsT | 1036224..1036472 (+) | 249 | WP_104967887.1 | 30S ribosomal protein S20 | - |
| P7F70_RS05275 (P7F70_05275) | ciaH | 1036949..1038253 (-) | 1305 | WP_278023491.1 | HAMP domain-containing sensor histidine kinase | Regulator |
| P7F70_RS05280 (P7F70_05280) | ciaR | 1038246..1038917 (-) | 672 | WP_104967889.1 | response regulator transcription factor | Regulator |
| P7F70_RS05285 (P7F70_05285) | - | 1039163..1041697 (-) | 2535 | WP_218654372.1 | M1 family metallopeptidase | - |
| P7F70_RS05290 (P7F70_05290) | phoU | 1041819..1042472 (-) | 654 | WP_115130300.1 | phosphate signaling complex protein PhoU | - |
| P7F70_RS05295 (P7F70_05295) | pstB | 1042498..1043256 (-) | 759 | WP_104967892.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| P7F70_RS05300 (P7F70_05300) | pstB | 1043269..1044072 (-) | 804 | WP_104967893.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| P7F70_RS05305 (P7F70_05305) | pstA | 1044085..1044972 (-) | 888 | WP_104967894.1 | phosphate ABC transporter permease PstA | - |
| P7F70_RS05310 (P7F70_05310) | pstC | 1044962..1045897 (-) | 936 | WP_104967895.1 | phosphate ABC transporter permease subunit PstC | - |
| P7F70_RS05315 (P7F70_05315) | - | 1045907..1046773 (-) | 867 | WP_104967896.1 | phosphate ABC transporter substrate-binding protein PstS | - |
Sequence
Protein
Download Length: 223 a.a. Molecular weight: 25377.22 Da Isoelectric Point: 4.4478
>NTDB_id=810996 P7F70_RS05280 WP_104967889.1 1038246..1038917(-) (ciaR) [Streptococcus pluranimalium strain SP28]
MIKLLLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLTDHTIVYGNISVDTTINRVTVDGKEVEFLGKEFELLMY
FLQNQNVILPKTQIFDRLWGFDSDTTLSVVEVYVSKIRKKLKGTSFADHLQTLRSVGYILKDA
MIKLLLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLTDHTIVYGNISVDTTINRVTVDGKEVEFLGKEFELLMY
FLQNQNVILPKTQIFDRLWGFDSDTTLSVVEVYVSKIRKKLKGTSFADHLQTLRSVGYILKDA
Nucleotide
Download Length: 672 bp
>NTDB_id=810996 P7F70_RS05280 WP_104967889.1 1038246..1038917(-) (ciaR) [Streptococcus pluranimalium strain SP28]
ATGATAAAATTACTCTTGGTTGAAGATGATTTGAGTTTGTCCAATTCTGTATTTGATTTTCTGGATGATTTTGCAGATGT
GATGCAGGTCTTTGATGGGGAAGAAGGATTGTATGAAGCTGAATCTGGTGTTTATGATCTTATTTTACTAGATCTTATGC
TTCCAGAAAAAAATGGTTTTCAAGTGCTAAAAGAGCTTCGAGAAAAAGGGATAACAACACCTGTTTTAATTATGACAGCA
AAGGAAGGGTTGGATGATAAGGGACATGGTTTTGAGTTAGGAGCAGATGATTATTTAACTAAGCCATTTTATCTAGAAGA
ATTAAAAATGAGAATTCAAGCCTTACTTAAACGTTCTGGAAAGTTGACCGATCATACCATCGTATACGGTAATATTAGCG
TTGACACGACAATTAATCGTGTTACAGTAGATGGCAAAGAAGTAGAATTTTTAGGCAAAGAATTTGAATTGTTAATGTAC
TTTCTACAAAACCAAAATGTTATTTTACCTAAAACACAGATTTTTGATCGTTTATGGGGATTTGATAGCGATACAACACT
TTCGGTTGTTGAAGTTTATGTGTCAAAAATCCGTAAAAAACTTAAAGGAACGAGTTTTGCAGATCATTTACAGACTTTAA
GAAGTGTTGGTTATATTTTAAAAGATGCATAA
ATGATAAAATTACTCTTGGTTGAAGATGATTTGAGTTTGTCCAATTCTGTATTTGATTTTCTGGATGATTTTGCAGATGT
GATGCAGGTCTTTGATGGGGAAGAAGGATTGTATGAAGCTGAATCTGGTGTTTATGATCTTATTTTACTAGATCTTATGC
TTCCAGAAAAAAATGGTTTTCAAGTGCTAAAAGAGCTTCGAGAAAAAGGGATAACAACACCTGTTTTAATTATGACAGCA
AAGGAAGGGTTGGATGATAAGGGACATGGTTTTGAGTTAGGAGCAGATGATTATTTAACTAAGCCATTTTATCTAGAAGA
ATTAAAAATGAGAATTCAAGCCTTACTTAAACGTTCTGGAAAGTTGACCGATCATACCATCGTATACGGTAATATTAGCG
TTGACACGACAATTAATCGTGTTACAGTAGATGGCAAAGAAGTAGAATTTTTAGGCAAAGAATTTGAATTGTTAATGTAC
TTTCTACAAAACCAAAATGTTATTTTACCTAAAACACAGATTTTTGATCGTTTATGGGGATTTGATAGCGATACAACACT
TTCGGTTGTTGAAGTTTATGTGTCAAAAATCCGTAAAAAACTTAAAGGAACGAGTTTTGCAGATCATTTACAGACTTTAA
GAAGTGTTGGTTATATTTTAAAAGATGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ciaR | Streptococcus mutans UA159 |
87.444 |
100 |
0.874 |
| ciaR | Streptococcus pneumoniae Rx1 |
86.547 |
100 |
0.865 |
| ciaR | Streptococcus pneumoniae D39 |
86.547 |
100 |
0.865 |
| ciaR | Streptococcus pneumoniae R6 |
86.547 |
100 |
0.865 |
| ciaR | Streptococcus pneumoniae TIGR4 |
86.547 |
100 |
0.865 |
| covR | Lactococcus lactis subsp. lactis strain DGCC12653 |
35.841 |
100 |
0.363 |