Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   P8R99_RS10115 Genome accession   NZ_CP121160
Coordinates   1932065..1932754 (+) Length   229 a.a.
NCBI ID   WP_278043285.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1927065..1937754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R99_RS10090 - 1927492..1928871 (-) 1380 WP_000680112.1 potassium transporter TrkG -
  P8R99_RS10095 rsmG 1928886..1929599 (-) 714 WP_000188792.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  P8R99_RS10100 - 1929727..1930281 (+) 555 WP_000537056.1 LemA family protein -
  P8R99_RS10105 htpX 1930302..1931192 (+) 891 WP_000966821.1 zinc metalloprotease HtpX -
  P8R99_RS10110 - 1931297..1931830 (+) 534 WP_000927540.1 YceD family protein -
  P8R99_RS10115 covR 1932065..1932754 (+) 690 WP_278043285.1 response regulator transcription factor Regulator
  P8R99_RS10120 - 1932744..1934249 (+) 1506 WP_000791116.1 HAMP domain-containing histidine kinase -
  P8R99_RS10125 nrdR 1934398..1934877 (+) 480 WP_001203682.1 transcriptional regulator NrdR -
  P8R99_RS10130 - 1934877..1936052 (+) 1176 WP_017648255.1 DnaD domain protein -
  P8R99_RS10135 dnaI 1936049..1936951 (+) 903 WP_000843624.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26563.55 Da        Isoelectric Point: 4.8094

>NTDB_id=810696 P8R99_RS10115 WP_278043285.1 1932065..1932754(+) (covR) [Streptococcus agalactiae strain S5]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGSDDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=810696 P8R99_RS10115 WP_278043285.1 1932065..1932754(+) (covR) [Streptococcus agalactiae strain S5]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTTTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGATCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGGGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGCGGTA
GTTTCCGTGATTTATCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.039

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.789

99.563

0.655
  vicR Streptococcus mutans UA159

45.455

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.432