Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   P8R98_RS03740 Genome accession   NZ_CP121159
Coordinates   722984..723673 (+) Length   229 a.a.
NCBI ID   WP_000516681.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 717984..728673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R98_RS03715 - 718411..719790 (-) 1380 WP_000680110.1 potassium transporter TrkG -
  P8R98_RS03720 rsmG 719805..720518 (-) 714 WP_000188798.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  P8R98_RS03725 - 720646..721200 (+) 555 WP_000537054.1 LemA family protein -
  P8R98_RS03730 htpX 721221..722111 (+) 891 WP_000966818.1 zinc metalloprotease HtpX -
  P8R98_RS03735 - 722216..722749 (+) 534 WP_000927544.1 YceD family protein -
  P8R98_RS03740 covR 722984..723673 (+) 690 WP_000516681.1 response regulator transcription factor Regulator
  P8R98_RS03745 - 723663..725168 (+) 1506 WP_000791105.1 HAMP domain-containing histidine kinase -
  P8R98_RS03750 nrdR 725317..725796 (+) 480 WP_001203682.1 transcriptional regulator NrdR -
  P8R98_RS03755 - 725796..726971 (+) 1176 WP_000074512.1 DnaD domain protein -
  P8R98_RS03760 dnaI 726968..727870 (+) 903 WP_278043502.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26547.55 Da        Isoelectric Point: 4.8094

>NTDB_id=810610 P8R98_RS03740 WP_000516681.1 722984..723673(+) (covR) [Streptococcus agalactiae strain S1]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=810610 P8R98_RS03740 WP_000516681.1 722984..723673(+) (covR) [Streptococcus agalactiae strain S1]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGCGGTA
GTTTCCGTGATTTATCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTATTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGTTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.887

100

0.463
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437