Detailed information NTG0809890

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: QN328_RS10415
• Genome accession: NZ_CP135102
• Coordinates: 2046229..2047227 (+)
• Length: 332 a.a.
• NCBI ID: WP_000196634.1
• Uniprot ID: Q8E2D9
• Organism: Streptococcus agalactiae strain HU32/21
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2041229..2052227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN328_RS10395 (QN328_10375)	-	2041333..2042576 (+)	1244	Protein_1974	DUF4041 domain-containing protein	-
QN328_RS10400 (QN328_10380)	-	2042708..2043553 (+)	846	WP_000613836.1	hypothetical protein	-
QN328_RS10405 (QN328_10385)	purB	2043571..2044869 (+)	1299	WP_410530731.1	adenylosuccinate lyase	-
QN328_RS10410 (QN328_10390)	comR	2045021..2045932 (+)	912	WP_000912100.1	helix-turn-helix domain-containing protein	Regulator
QN328_RS10415 (QN328_10395)	ruvB	2046229..2047227 (+)	999	WP_000196634.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
QN328_RS10420 (QN328_10400)	-	2047379..2047816 (+)	438	WP_000754813.1	low molecular weight protein-tyrosine-phosphatase	-
QN328_RS10425 (QN328_10405)	-	2047823..2048203 (+)	381	WP_000787700.1	membrane protein	-
QN328_RS10430 (QN328_10410)	-	2048200..2049978 (+)	1779	WP_001220909.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37557.94 Da
• Isoelectric Point: 4.5391

>NTDB_id=809890 QN328_RS10415 WP_000196634.1 2046229..2047227(+) (ruvB) [Streptococcus agalactiae strain HU32/21]
MTRFLDSDAMGDEELVERTLRPQYLREYIGQDKVKDQLKIFIEAAKLRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAIEKSGDLVAILNDLEPGDVLFIDEIHRMPMAVEEVLYSAMEDFYIDIMIGAGETSRSVHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYEENDLTEIIERTADIFEMKITYEAASELARRSRGTPRIANRLLKRVRDYAQIMGDGLID
DNITDKALTMLDVDHEGLDYVDQKILRTMIEMYNGGPVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVATVK
AYEHLGYQRFDK

Nucleotide

• Length: 999 bp

>NTDB_id=809890 QN328_RS10415 WP_000196634.1 2046229..2047227(+) (ruvB) [Streptococcus agalactiae strain HU32/21]
ATGACAAGATTTTTAGATAGTGATGCAATGGGTGACGAAGAATTGGTAGAACGTACACTTCGTCCGCAGTATTTAAGAGA
GTATATTGGACAAGATAAGGTTAAAGATCAGCTAAAAATATTTATTGAAGCTGCTAAATTGCGTGATGAGTCATTGGATC
ATGTGTTATTATTTGGCCCTCCTGGTTTAGGGAAAACAACCATGGCATTTGTAATTGCTAATGAGTTGGGTGTCAATCTC
AAACAAACATCAGGTCCCGCAATTGAAAAATCAGGGGATTTAGTAGCCATTTTAAATGATTTAGAACCAGGTGATGTTCT
TTTTATTGATGAAATTCATCGTATGCCGATGGCGGTTGAAGAGGTACTTTATAGTGCAATGGAAGACTTCTATATTGACA
TTATGATCGGTGCAGGAGAAACTAGTAGAAGTGTTCATCTAGATTTGCCGCCCTTTACCTTAATTGGTGCAACGACACGT
GCAGGTATGTTATCTAATCCCTTACGTGCTCGCTTTGGTATTACAGGGCATATGGAGTATTATGAAGAAAATGATTTGAC
AGAAATTATTGAGCGTACAGCAGACATTTTTGAAATGAAAATTACTTATGAAGCTGCTTCTGAATTAGCGCGTCGCAGTC
GTGGAACGCCACGTATCGCTAACCGTTTATTGAAACGTGTTCGAGATTATGCTCAAATCATGGGAGATGGTTTGATAGAT
GACAATATTACAGATAAAGCATTAACGATGTTAGATGTTGATCACGAGGGGCTTGATTACGTCGATCAAAAAATCTTAAG
AACCATGATTGAAATGTATAATGGAGGTCCTGTTGGTTTAGGAACTCTATCCGTTAATATTGCTGAAGAACGAGATACTG
TTGAAGACATGTACGAACCTTATTTAATTCAAAAAGGTTTTATTATGCGTACCCGTACCGGTCGTGTAGCTACGGTTAAG
GCATATGAACATTTAGGTTATCAGCGATTTGATAAATAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

3D structure

• AlphaFold DB: Q8E2D9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae TIGR4	90.06	100	0.901
ruvB	Streptococcus pneumoniae R6	89.759	100	0.898
ruvB	Streptococcus pneumoniae D39	89.759	100	0.898
ruvB	Bacillus subtilis subsp. subtilis str. 168	59.819	99.699	0.596
ruvB	Helicobacter pylori 26695	53.074	93.072	0.494
ruvB	Synechocystis sp. PCC 6803	50.479	94.277	0.476